160 results match your criteria: "Dermoid Limbal"
Managing Limbal Dermoids in Patients with Goldenhar Syndrome: A Case Series.
Rom J Ophthalmol
October 2024
ENT Department, Military Hospital, Jammu, J&K, India.
Objective: To investigate the clinical characteristics, associated systemic features, and management outcomes of patients with limbal dermoids diagnosed with Goldenhar syndrome.
Methods: This case series included patients from the eye outpatient department, diagnosed with Goldenhar syndrome based on systemic evaluation. Demographic data, ophthalmological assessments, and systemic evaluations were recorded.
Several problems differentiate the treatment of children, especially those with congenital ocular disease, from adults, including the absence of complaints and the complication of systemic diseases. However, the most challenging is the continuing developing anatomical and functional development and immaturity in children. Consequently, the timing of disease onset and treatment can greatly affect the prognosis, and the prognosis cannot be confirmed without long-term follow-up periods.
View Article and Find Full Text PDFChanging indications for and trends of keratoplasty in a tertiary comprehensive hospital in northern part of China from 2002 to 2021: a 20-year review.
BMC Ophthalmol
October 2024
Beijing Ophthalmology & Visual Science Key Laboratory, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China.
Article Synopsis
- - The study analyzed 20 years of keratoplasty procedures at a major hospital in northern China, reviewing 8,266 cases from 2002 to 2021 to identify trends in surgical indications and techniques.
- - The most common reasons for keratoplasty were keratoleukoma, regraft, corneal endothelial dysfunction, and keratoconus, with a significant decrease in keratoleukoma cases and an increase in corneal endothelial dysfunction, regrafts, and congenital corneal opacities over time.
- - A major change was noted in surgical methods, with penetrating keratoplasty declining and both anterior lamellar keratoplasty and endothelial keratoplasty becoming more popular, particularly in patients with cor
A Retrospective Analysis of Corneal Dermoid.
Cureus
July 2024
Henan Eye Institute, Henan Provincial People's Hospital, People's Hospital of Henan University, First Affiliated Hospital of Zhengzhou University, Zhengzhou, CHN.
Article Synopsis
- Corneal dermoid is a benign congenital tumor often identified in early childhood, but there’s limited research on its treatment and long-term outcomes.
- This study examined 58 patients treated for corneal dermoid between 2017 and 2021, collecting data on demographics, tumor features, surgical methods, and post-surgery results.
- Findings revealed that most patients were young, with the right eye most commonly affected, and post-surgery, 58% showed improved vision, highlighting the effectiveness of various surgical approaches.
Goldenhar syndrome with limbal neoformation, microtia and skeletal deformities: a case report and literature review.
BMC Ophthalmol
February 2024
Department of Ophthalmology, the Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China.
Article Synopsis
- - The case report discusses a 4-year-old boy diagnosed with Goldenhar syndrome, characterized by multiple malformations such as a limbal dermoid, bilateral microtia, and ear canal deformities.
- - Diagnostic imaging revealed additional issues like maxillofacial abnormalities and scoliosis, while genetic testing indicated possible gene variations linked to microtia.
- - Goldenhar syndrome is a rare congenital condition that requires a multidisciplinary approach for effective diagnosis and treatment, highlighting the need for specialists like otolaryngologists and craniofacial surgeons.
Sutureless lamellar keratoplasty with lenticule from small incision lenticule extraction for treating limbal dermoid: A case report.
Exp Ther Med
February 2024
Department of Ocular Surface and Refraction, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi 046000, P.R. China.
Article Synopsis
- This study discusses a new surgical technique for treating a superficial limbal dermoid using lamellar keratoplasty without stitches, incorporating an allogenic lenticule from a small incision method.
- The technique involves careful removal of the dermoid and attaching a stromal lenticule directly to the implant bed, secured with a bandage contact lens instead of sutures or glue.
- Postoperative results were positive, with improvement noted in corneal thickness, curvature, and patient satisfaction over three months, suggesting this method may be advantageous compared to traditional lamellar keratoplasty.
A retrospective study of conjunctival lesions in the Paediatric Eye Clinic over 12 years.
Eye (Lond)
February 2024
Royal Victoria Hospital, Belfast Health and Social Care Trust, Northern Ireland, UK.
Article Synopsis
- Pediatric conjunctival lesions are uncommon but can sometimes be serious and affect vision or health, so it's important to know when they could be a problem.
- A study looked at children in Belfast with these types of lesions over 12 years and found 85 cases, with the most common types being naevi and limbal dermoids.
- Some lesions were treated right away, while others were watched over time, and careful monitoring can help catch any dangerous changes early on.
Birth prevalence and characteristics of congenital corneal opacities.
Eur J Ophthalmol
May 2024
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO, USA.
Article Synopsis
- This study examined the prevalence and development of congenital corneal opacities in children under 5 in Olmsted County, Minnesota, over a 40-year period.
- The research found that the birth prevalence was 1 in 5188 live births, with a mean age of diagnosis at 7.5 months and 64.3% of the patients being male.
- Despite some patients needing treatment and experiencing issues like amblyopia and strabismus, the majority achieved good visual outcomes, with a median best corrected visual acuity of 20/25.
Lamellar Keratoplasty Using Microkeratome-Assisted Anterior Lamellar Graft in the Management of Deep Limbal Dermoid: A Case Report.
Turk J Ophthalmol
June 2023
Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Türkiye.
Article Synopsis
- Limbal dermoid is a benign tumor present at birth, typically found at the limbus (the border of the cornea and sclera) of the eye.
- Surgical intervention is often needed, especially for deeper lesions, which may involve tumor removal and procedures like amniotic membrane transplantation or corneal grafting.
- The text details a specific case where a deep limbal dermoid was successfully treated with surgery, including excision of the tumor and a lamellar keratoplasty using a specialized tool called a microkeratome.
Novel limbal dermoid surgery for visual acuity and cosmesis improvement: A 7-year retrospective review.
PLoS One
June 2023
Department of Ophthalmology, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea.
Article Synopsis
- The study looked at a new surgery for removing limbal dermoids, which are growths on the eye.
- 24 kids, about 10 years old, had this surgery and their eye appearance improved with no major problems.
- The surgery was safe and helped make their eyes look better, even though their eyesight didn't change much.
Treatment of corneal dermoid with lenticules from small incision lenticule extraction surgery: a surgery assisted by fibrin glue.
Int J Ophthalmol
April 2023
Department of Ophthalmology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Article Synopsis
- The study aimed to evaluate the effectiveness of using small incision lenticule extraction (SMILE)-derived patches for repairing the cornea after dermoid excision, with the patches secured using fibrin glue.
- Seventeen patients underwent this procedure, and over an average follow-up of about 11.5 months, the patches remained securely in place and clear, leading to significant improvements in best-corrected visual acuity (BCVA) for some patients.
- The technique was found to be safe, with some minor complications addressed effectively, and all participating patients reported satisfaction with the cosmetic results post-surgery.
Congenital limbal dermoid in a 10-year-old male.
Pan Afr Med J
April 2023
Department of Ophthalmology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher education and Research, Sawangi (Meghe), Wardha, Maharashtra, India.
Diagnosing Corneal Pigmentation in Small Animals.
Vet Clin North Am Small Anim Pract
March 2023
Antech Diagnostics, 7555 Danbro Crescent, Mississauga, Ontario L5N 6P9, Canada.
Article Synopsis
- The cornea needs to be transparent for proper light transmission, and any loss of this transparency can lead to vision problems.
- Corneal pigmentation happens when melanin builds up in the cornea's epithelial cells, and various conditions like corneal sequestrum and limbal melanocytoma need to be ruled out to diagnose it accurately.
- Multiple eye surface issues, including tear film deficiency and breed-related syndromes, can be linked to corneal pigmentation, so it's essential to pinpoint the exact cause for effective treatment.
Technique for the Management of Extensive Ocular Surface Lipodermoid Involving the Cornea of Children.
Cornea
June 2023
Division of Paediatric Ophthalmology, Strabismus, and Adult Motility, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.
Article Synopsis
- The study focuses on a staged surgical technique for treating large ocular surface lipodermoids, which may affect vision and eyelid closure in children.
- The procedure involves debulking the conjunctival part of the lipodermoid, followed by excising the corneal section and performing autologous limbal epithelial transplantation to aid healing.
- Results from three pediatric cases showed significant improvement in visual axis clearance and eyelid function, with minimal complications, suggesting this method as a viable alternative to more invasive options.
Preoperative geometric parameters predict the outcome of lamellar keratoscleroplasty in patients with limbal dermoids.
Int Ophthalmol
July 2023
Joint Shantou International Eye Center of Shantou University, The Chinese University of Hong Kong, Dongxia Road, Shantou, 515041, Guangdong Province, People's Republic of China.
Article Synopsis
- The study aimed to identify simple geometric parameters that can predict the surgical outcomes of lamellar keratoscleroplasty in patients with corneal limbal dermoids.
- A total of 30 patients were analyzed, focusing on seven specific geometric metrics related to the dermoid and their impact on postoperative visual acuity, astigmatism, and scarring.
- Key findings indicated that the length of the dermoid invading the cornea was significantly associated with both improved visual acuity and astigmatism after surgery, especially in patients with amblyopia.
Astigmatic reduction after dermoid excision in a child with Goldenhar syndrome.
Med J Armed Forces India
January 2023
Specialist (Pathology), Tata Main Hospital, Jamshedpur, Jharkhand, India.
Article Synopsis
- Goldenhar syndrome is a rare birth condition that can cause problems with the eyes and face.
- A three-year-old girl with this syndrome had a growth in her eye called a limbal dermoid, which made it hard for her to see.
- After surgery to remove the growth, her eyesight improved a lot, showing that early treatment can help kids see better and look good too!
SCALP syndrome with a germline heterozygous DOCK6 mutation and somatic mosaic NRAS Q61R mutation.
Pediatr Dermatol
May 2023
Department of Dermatology, University of California Davis, Sacramento, California, USA.
Article Synopsis
- The text discusses a case of SCALP syndrome diagnosed in a male infant, featuring symptoms like sebaceous nevi and CNS malformations.
- The study identified specific genetic mutations linked to the syndrome, including a DOCK6 mutation and a NRAS mutation in the nevus.
- This report aims to enhance awareness among clinicians regarding SCALP syndrome and contribute to the understanding of its genetic characteristics.
Multimodal ocular imaging in Proteus syndrome.
Eur J Ophthalmol
September 2023
Ophthalmology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy.
Article Synopsis
- - The report discusses the ophthalmologic assessment of two patients with Proteus Syndrome, showcasing their unique eye-related health issues.
- - Case #1 is a 26-year-old male with multiple vision problems, including cataracts and severe myopia, while Case #2 is a 20-year-old female evaluated after treatment with an experimental drug.
- - Both patients underwent thorough eye examinations and multimodal imaging, which proved beneficial for detailing their conditions and tracking disease progression over time.
Circumscribed choroidal hemangioma in a case of neurofibromatosis type 1.
Oman J Ophthalmol
June 2022
Shri Bhagwan Mahavir, Department of Vitreo Retina Services and Ocular Oncology, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.
Refractive Characteristics and Related Factors of Amblyopia after Lamellar Keratoscleroplasty in Children with Limbal Dermoids.
J Clin Med
July 2022
Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Article Synopsis
- The study focused on analyzing the refractive properties and factors related to amblyopia in children with limbal dermoids who underwent lamellar keratoscleroplasty.
- It involved 41 pediatric patients, assessing various metrics like cycloplegic refraction, corneal topography, and the size of limbal dermoid invasion, which appeared to affect the severity of amblyopia.
- Results indicated that high hyperopia and astigmatism were common refractive errors, showing a significant correlation between postoperative visual acuity, age, treatment duration, and the severity of astigmatism.
Visual and surgical outcomes of limbal dermoid excision at a tertiary care eye hospital.
Eur J Ophthalmol
January 2023
Research Department, 46670King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Article Synopsis
- The study assessed patient complaints, surgical methods, outcomes, complications, and visual acuity after limbal dermoid excision over an 8-year period.
- A total of 51 eyes from 50 patients were examined, with a variety of surgical techniques employed, including excision and corneal transplant options.
- While most patients exhibited good visual outcomes post-surgery, there was a notable incidence of postoperative astigmatism, indicating a need for ongoing monitoring and potential treatment.
Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome.
Clin Genet
September 2022
Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany.
Article Synopsis
- Proteus syndrome is a rare disorder characterized by uneven and disproportionate growth of different body parts, often with varying symptoms, and is linked to a mutation in the AKT1 gene.
- A case study discusses a girl with a progressive lipoma in her skull and other mild symptoms who didn't meet the full criteria for Proteus syndrome, yet a genetic test confirmed the presence of the AKT1 mutation.
- The study suggests that even if a patient shows mild symptoms, they may still have oligosymptomatic Proteus syndrome, which has implications for genetic counseling and potential treatments using AKT1 inhibitors instead of just surgeries.
Effects of Perceptual Learning on Deprivation Amblyopia in Children with Limbal Dermoid: A Randomized Controlled Trial.
J Clin Med
March 2022
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou 510060, China.
Article Synopsis
- Limbal dermoid (LD) is a congenital eye tumor that negatively impacts visual acuity (VA) and can lead to amblyopia in children.
- The study involved 25 children with LD and 25 normal children, assessing their contrast sensitivity function (CSF) and VA, finding significant deficits in the LD group.
- Perceptual learning (PL) combined with patching was more effective in improving both CSF and VA than patching alone over a 6-month period.
Successful Management of Limbal Dermoid in Infancy and Childhood: A Case Series.
Cureus
March 2022
College of Medicine, Umm Al-Qura University, Makkah, SAU.
Article Synopsis
- This study looks at five cases of a condition called limbal dermoid in kids, including one who also had a syndrome called Goldenhar.
- Limbal dermoid can cause problems with vision, like astigmatism, which can lead to something called amblyopia (lazy eye).
- Surgery to remove concerned limbal dermoids is important, and kids may also need treatment like glasses or patching to help their vision.