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The aim of this work is to study the indexes of immune status and level of endogenous intoxication in patients with acne disease, which have got medicinal and complex treatment with using ozone-oxygen mixture (OOM). After complex course of treatment positive changes have happened in regulatory systems - in indexes of cellular and humoral immunity. The treatment with using OOM enabled earlier normalization of absolute and percentage content of T-lymphocytes, removed immunodeficiency of suppressor and helper population of T-lymphocytes, decreased circulating immune complexes, amount of B-lymphocytes.
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