Navigated three-dimensional intraoperative ultrasound-guided awake resection of low-grade glioma partially infiltrating optic radiation.

We report a case of awake resection of temporal low-grade glioma infiltrating the optic radiation (OR). The OR was localized by direct electrical stimulation (DES) and the tumor was delineated by navigated intraoperative 3D ultrasound. Ultrasound artifacts were eliminated by 3D-ultrasound data acquisition with a miniature probe inserted into the resection cavity.

Vascular complications after renal transplantation.

Background: Vascular complications in renal transplant recipients are uncommon but important causes of graft dysfunction and graft loss after kidney transplantation.

Objectives: To document vascular complications that occurred following kidney transplantations in order to assess the incidence of these complications at our center as well as to identify possible treatment approach.

Methods: 103 kidney transplantations were performed in the period from 1 January 2008 to 31 December 2009.

New approach to probability estimate of femoral neck fracture by fall (Slovak regression model).

Patients And Methods: 3,216 Slovak women with primary or secondary osteoporosis or osteopenia, aged 20-89 years, were examined with the bone densitometer DXA (dual energy X-ray absorptiometry, GE, Prodigy - Primo), x = 58.9, 95% C.I.

Why is it so important to balance the muscular dysbalance in mm. coxae area in osteoporotic patients?

The article presents a biomechanical model of articulatio and mm. coxae with the characteristics of the vectors of reaction forces generated in flexors and extensors (1) in muscular balance; (2) in muscular dysbalance; (2a) with permanent load of the model of a hip by the body weight; (2b) with simulated live load during a fall or an impact. In case of muscular dysbalance the application of action force on a hip during a fall results in a sharp increase of the reaction compressive force in flexors and the tensile force in extensors.

Biomechanical conditions for maintaining body balance in kinesitherapy of osteoporotic patients.

Regularities of mechanical conditions of body's static and dynamic balance are applied not only in movement techniques of sports events, but also in setting up exercises for osteoporotic patients. It is important to set up exercises in which the patient takes such a position where the forces acting upon him (action forces) are in balance with the forces generated in the patient's musculoskeletal system (reaction forces). On the basis of biomechanical analysis of conditions for maintaining a trainee's body balance in training position, we point out the importance of individual exercise in sitting and prone positions led by a rehabilitation instructor, aiming at the removal of muscular dysbalance, before including the patient in group exercise.

Nordic walking--is it suitable for patients with fractured vertebra?

This article brings the biomechanical analysis of sport--Nordic walking--for patients with osteoporotic fractured vertebrae and shows that it is suitable for them. Based on the biomechanical model of skeletal load we have developed a method of walking movement for patients, different from the method of walking movement for healthy people. And so came into being the "first sport" for patients with osteoporotic fractures.

The effect of severe hepatic impairment on the pharmacokinetics and haematological response of C.E.R.A.

Aim: To examine the effect of severe hepatic impairment (HI) on the pharmacokinetics (PK) and pharmacodynamics (PD) of the continuous erythropoietin receptor activator, C.E.R.

Coxsackie B virus infection of mice: inoculation by the oral route protects the pancreas from damage, but not from infection.

The pathogenesis of coxsackie B virus (CVB) infections is generally studied in mice by intraperitoneal (i.p.) injection, whereas the gastrointestinal tract is the natural porte d'entrée in humans.

Different patterns of serum interleukin 10 response to treatment with anti-tumor necrosis factor alpha antibody (infliximab) in Crohn's disease.

Administration of anti-tumor necrosis factor antibody (anti-TNF, infliximab) down-regulates T helper 1 (Th 1) cytokines production in intestinal mucosa of patients with Crohn's disease (CD). Interleukin 10 (IL-10) is thought to be involved in CD pathogenesis through regulation of the Th 1 response. The aim of this study was to determine the IL-10 response in CD patients treated with anti-TNF.

Changes in acute phase proteins after anti-tumor necrosis factor antibody (infliximab) treatment in patients with Crohn's disease.

Acute phase proteins and markers of proteosynthetic activity reflect the clinical activity in Crohn's disease (CD). The impact of anti-tumor necrosis factor antibody (anti-TNF) therapy on serum levels of acute phase proteins and proteosynthetic markers was studied. Fourteen patients with active CD were treated with 5 mg per kg of anti-TNF in intravenous infusion.

Nuchal fibrocartilaginous pseudotumor: immunohistochemical and ultrastructural study of two cases.

Two cases of nuchal fibrocartilaginous pseudotumor are reported. The lesions occurred in a 50-year-old woman and a 41-year-old man. From the clinical point of view, the absence of history of trauma in one case represents an unusual observation.

Low-grade fibromyxoid sarcoma: a report of eight cases with histologic, immunohistochemical, and ultrastructural study.

We present eight cases of low-grade fibromyxoid sarcoma (LGFS) of soft tissues. The patients, six men and two women, ranged in age from 28 to 44 years (median, 39 years). All tumors were subcutaneous.

[Comprehensive treatment of crural ulcers].

The authors present 65 patients treated in the stage C6 of chronic venous insufficiency. Conservative therapy was performed in the cases with large ulcers associated with crural edema. Recovery was observed in 47 cases (73%) during 5 months.

[Prophylactic effects of ceftriaxone in patients after endoscopic papillosphincterotomy].

In thirty patients after EPS and gall extraction for cultivation ceftriaxon in preventive dose 1 g was administered. This group of patients was compared with a group of 30 patients after EPS without preventive administration of antibiotic from clinical and biochemical point of view. Most frequently occurring bacteria in the gall of patients after EPS were Pseudomonas aeruginosa and E.

Computerized brain atlas in functional neurosurgery.

Computerized brain atlas is a new application area in the practical use of stereotactic neurosurgery. Our approach provides a solution for the straightforward definition of a coordinate system (CA-CP), localization of the selected target point, trepanation points and trajectory transformation of the stereotactic electrode or canula for functional neurosurgery. These problems were solved by comparison of CT, MR and the Schaltenbrand-Wahren atlas.

Tubular basement membrane thickening in diabetes mellitus.

Authors measured the thickness of the basement membranes of the proximal and distal tubuli in the renal cortex in 20 patients with verified diabetes mellitus. The test group consisted of 20 patients with small abnormalities of glomeruli (or in the range of variable norm), of the same sex and comparable age. Measurements were performed in locations without tubulo-interstitial changes.

Combination warp-matching method for stereotactic neurosurgery.

Digital image warping is a growing branch of image processing that deals with geometric transformation techniques. A geometric transformation is an operating that redefines the spatial relationship between points in an image. Physically based modeling is a field strongly attracting research interest in recent years.

Prevalence of Lyme borrelia in ticks in Bratislava, Slovak Republic.

A total of 2857 unfed Ixodes ricinus adult ticks were collected in 2-3 week intervals in 1991 in Bratislava to survey their prevalence with spirochaetes. Five hundred twenty eight, i.e.

Late responses after transcranial magnetic stimulation in stroke.

In addition to early responses after transcranial magnetic stimulation, usually designated as Motor Evoked Potentials (MEP), several late responses have been reported in intervals up to 500 ms following stimulus. Our attention in this work was focused on the response in interval 150-300 ms after stimulus output, which is also designated as S > 150 response. We monitored longitudinally late S > 150 response in group of 19 stroke patient with verified hemispherical ischemic lesion.

Brainstem auditory evoked potentials (BAEPs) pathology in topographical diagnosis of posterior fossa lesions.

The authors tried to determine the level of the brainstem where possible generators of various BAEPs waves could be situated by correlating clinical neurological symptomatology and/or cranial computed tomography findings of 195 patients with posterior fossa lesions with distinct BAEPs waves pathology. Results of statistical analysis showed a significant dependence between the levels of lesions as revealed by clinical symptomatology and/or cranial computed tomography and distinct BAEPs waves I-V pathology. Only indirect proof exists for the supratentorial origin of waves VI and VII.

MR-guided stereotaxy in functional neurosurgery.

MR imaging enables the localization of the anteroposterior commissural line, but sometimes it is difficult to define the anterior commissure point. The corpus callosum is more easily identified in this case. We performed an MR imaging using the following methodology; a single transverse scan from which a coronal scan is planned with compensation.

Orchiectomy alone for clinical stage I nonseminomatous germ cell tumors of the testis (NSGCTT): a minimum follow-up period of 5 years.

Aims And Background: Surveillance after orchiectomy alone has gained great popularity in the management of stage I NSGCTT. Preliminary results were enthusiastic, but critical voices have been raised against general use of this option as routine management. In an effort to identify patients at high risk of relapse, there has been a search for adverse prognostic factors of stage I nonseminomatous germ cell testicular tumors (NSGCTT).