1 results match your criteria: "Department of Vascular Medicine Amsterdam University Medical Centerslocation AMCUniversity of Amsterdam Netherlands.[Affiliation]"
Low-Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific.
J Am Heart Assoc
June 2022
Article Synopsis
- Women generally have a lower risk of cardiovascular disease (CVD) compared to men, but this study investigates how genetically increased low-density lipoprotein cholesterol (LDL-C) affects CVD differently in each sex.
- Using data from over 425,000 participants from the UK Biobank, researchers created a genetic score to analyze the impact of LDL-C on various cardiovascular outcomes.
- Findings indicated that while women experience a larger LDL-C increase from genetic factors, their risk for CVD is lower than that of men, highlighting sex-specific differences in how LDL-C influences cardiovascular health.