1,400 results match your criteria: "Department of VMMC & Safdarjung Hospital[Affiliation]"

Many studies showed Vitamin D deficiency is highly prevalent in healthy individuals. We planned to study the normal levels of Vitamin D in healthy individuals and make recommendation for defining deficiency of 25(OH)D in Indian population. ormal healthy subjects 18 to 60 years of age were included.

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Navigating Hyperkalaemia- The A-to-H Clinical Strategy.

J Pak Med Assoc

January 2025

Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India.

Hyperkalaemia is a life-threatening dyselectrolytaemia which is characterized by elevated serum potassium levels. It needs a systematic and overarching approach to effectively manage a case of hyperkalaemia. We propose a structured A-to-H approach to guide clinicians in managing hyperkalaemia, ensuring that no critical aspect is neglected or inadvertently missed.

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Objectives: The literature does not show any studies that correlate between the morphological parameters of knee and functional outcome after anterior cruciate ligament reconstruction. The purpose of this study was to establish a correlation of morphological parameters of the knee in (magnetic resonance imaging) MRI with functional outcome in patients who underwent anterior cruciate ligament reconstruction.

Material And Methods: This was an observational study which included 63 patients who underwent anterior cruciate ligament reconstruction.

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User satisfaction with Assistive Technology (AT) is one of the crucial factors in the success of any AT service. The current study aimed to estimate satisfaction with AT and the reasons for dissatisfaction and unsuitability among persons with functional difficulties in India. Using the WHO Rapid Assistive Technology Assessment tool, a cross-sectional study was conducted in eight districts, representing four zones of India.

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Introduction Effective postoperative analgesia following lower segment cesarean section (LSCS) is crucial for promoting surgical recovery and fostering maternal-neonatal bonding. This study aimed to compare the efficacy of two IV dexamethasone doses (8 mg and 4 mg) in managing postoperative pain in LSCS patients. The objective was to assess whether the 4 mg dose provides comparable pain relief to the 8 mg dose, with the goal of identifying the optimal dosage for effective pain management with minimal side effects.

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 Diwali is a festival that is passionately celebrated by Indians all across the globe. Fire hazards associated with this festival are well known. Our hospital is a tertiary care burn center and caters to a patient population from all over North India.

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Campaigns to scale up Voluntary Medical Male Circumcision (VMMC) for the prevention of HIV transmission has been going on for years in selected Southern African countries, following recommendations from the World Health Organisations. Despite significant strides made in the initiative and its proven benefits, controversies surrounding the strategy have never ceased, and its future remains uncertain especially as some countries near their initial targets. Over the years, as the campaigns unfolded, a lot of insights have been generated in favour of continuing the VMMC campaigns, although some insights portray the impression that the strategy is not worthy of the risks and effort required, or that enough has been done, as the targets have now been achieved.

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Voluntary medical male circumcision (VMMC) was identified as an effective strategy in HIV prevention. Although circumcision reduces heterosexual acquisition of HIV by 60%, there is low uptake of VMMC services in Eswatini. This study applies the health belief model (HBM) in understanding perceptions of young men in Eswatini towards VMMC for HIV prevention to upscale its adoption.

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Frailty is an age-associated state of increased vulnerability due to declines in physiologic systems, leading to compromised ability to withstand stressors. Given India's rapidly aging population, our study aims to estimate the pooled prevalence of frailty and its associated factors in hospital settings. An extensive search was conducted across four databases, up to January 2024.

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Objective: Artificial intelligence (AI) has been increasingly utilized in diagnosis of skeletal deformities, while its role in treatment planning and outcome prediction of jaw corrective surgeries with 3-dimensional (3D) imaging remains underexplored.

Methods: The comprehensive search was done in PubMed, Google scholar, Semantic scholar and Cochrane Library between January 2000 and May 2024. Inclusion criteria encompassed studies on AI applications in treatment planning and outcome prediction for jaw corrective surgeries using 3D imaging.

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Mathematical modelling has played an increasingly prominent role in public health responses, for example by offering estimates of how infectious disease incidence over time may be affected by the adoption of certain policies and interventions. In this paper, we call for greater research and reflection into the ethics of mathematical modeling in public health. First, we present some promising ways of framing the ethics of mathematical modeling that have been offered in the very few publications specifically devoted to this subject.

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Introduction: Preeclampsia and eclampsia are hypertensive disorders of pregnancy associated with significant maternal and fetal morbidity and mortality. Posterior reversible encephalopathy syndrome (PRES) is a neurological complication observed in these conditions, yet its impact on fetomaternal outcomes remains underexplored. The aim of this study is to investigate the association between PRES and fetomaternal outcomes in women with preeclampsia and eclampsia.

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Up to 98% of adult voluntary medical male circumcision (VMMC) clients heal without adverse events (AEs) in South Africa and in the sub-Saharan Africa (SSA) region, yet all clients in South Africa (SA) are still required to attend in-person reviews, creating added work for providers and barriers for clients. A randomized controlled trial (RCT) using our fee-free, open-source, two-way texting (2wT) approach showed that males could independently monitor their healing with support from VMMC nurse-led telehealth and that 2wT was more cost-effective than routine visits for quality post-operative monitoring. The objectives of this costing activity were to assess the additive cost of 2wT vs.

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Introduction: Tuberculosis (TB) continues to be one of the deadliest infectious diseases over the centuries, killing more people worldwide than any other single infectious disease. There is an urgent need for additional strategies which can expedite efforts to combat TB including a preventive vaccine. In this endeavour, we have developed a protocol for a multisite, double-blind, placebo-controlled clinical trial in India that aims to evaluate the efficacy and safety of two TB vaccines; namely, VPM1002 and Immuvac () () (MIP) among healthy household contacts (HHCs) of sputum smear-positive pulmonary TB (PTB) patients.

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Introduction: Caudal block is an effective regional anesthesia technique for perineal surgeries but is associated with various adverse effects. Recently, pudendal nerve block has emerged as a promising alternative for these procedures. This study assessed the effectiveness of a novel transperineal technique for ultrasound-guided pudendal nerve block and compares it with ultrasound-guided caudal block for perineal surgeries in pediatric patients.

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Article Synopsis
  • Tight junctions (TJs) act as barriers in cells and have numerous proteins associated with them, yet TJs in the male genital tract are not well-researched due to limited tissue availability.
  • The study involved analyzing 132 TJ genes from foreskin tissue of men undergoing voluntary medical male circumcision as part of a larger HIV prevention trial in South Africa and Uganda, measuring the impact of various PrEP drugs on TJ protein expression.
  • Results showed that 118 out of 132 TJ genes were highly expressed in foreskin tissue, and that the PrEP regimens tested did not alter TJ gene expression or protein levels, indicating the safety of these treatments in preventing HIV-1 transmission during sexual activity.
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Several Genome Wide linkage Studies on psoriasis performed to gain insight of genetic architecture of the disease. Caspase Recruitment Domain-containing family 14 (CARD14) also known as CARMA2 or BIMP2; cytogenic location: 17q25.3, is a scaffold protein that primarily controls the skin epidermis's nuclear factor kB (NF-kB) signaling pathway activity in skin epidermis, a master gene for inflammation, has been shown to be linked with rare, heritable form of psoriasis.

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Unlabelled: Gustation is affected in patients of Chronic rhinosinusitis (CRS) depending on severity of diseases. This study aimed to find the prevalence of gustatory dysfunction in patients with CRS. This case-control study included 61 patients with CRS and 61 healthy controls.

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Voluntary medical male circumcision (VMMC) is a recommended HIV prevention strategy that few studies have promoted to HIV-negative men in serodiscordant relationships. We conducted a cross-sectional study on uptake and perceptions of VMMC among serodiscordant couples between 2012 and 2015. Heterosexual couples attending couples voluntary counselling and testing for HIV who had discordant results (M-, F+) were referred for VMMC.

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Article Synopsis
  • The study aimed to find out how common chronic liver disease is among adult Asian Indians using ultrasound shear wave elastography (SWE) in preventive radiology clinics.
  • Researchers measured liver stiffness in 1,145 participants and found that about 10.65% had advanced chronic liver disease, with 22.79% showing signs suggestive of this condition.
  • The findings highlight that chronic liver disease is linked to various comorbidities and risk factors, indicating a need for preventative strategies based on liver stiffness measurements.
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The objective is to minimize the inaccuracies in two-step impressions by homogenizing the polymerization shrinkage of elastomeric impression material in fixed prosthesis fabrication. The objective is accomplished by the technique of spacer adaptation and custom tray fabrication for two-step impressions. The technique makes the use of two vacuum-adapted spacers, selected based on the viscosity of elastomeric impression, and a vacuum-adapted custom tray.

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