6 results match your criteria: "Department of Translational Medicine Lund University Skåne University Hospital Malmö Sweden.[Affiliation]"
Article Synopsis
- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
- In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
- There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
Digital breast tomosynthesis in mammographic screening: false negative cancer cases in the To-Be 1 trial.
Insights Imaging
February 2024
Section for Breast Cancer Screening, Cancer Registry of Norway, Oslo, Norway.
Objectives: The randomized controlled trial comparing digital breast tomosynthesis and synthetic 2D mammograms (DBT + SM) versus digital mammography (DM) (the To-Be 1 trial), 2016-2017, did not result in higher cancer detection for DBT + SM. We aimed to determine if negative cases prior to interval and consecutive screen-detected cancers from DBT + SM were due to interpretive error.
Methods: Five external breast radiologists performed the individual blinded review of 239 screening examinations (90 true negative, 39 false positive, 19 prior to interval cancer, and 91 prior to consecutive screen-detected cancer) and the informed consensus review of examinations prior to interval and screen-detected cancers (n = 110).
Global Burden of Cardiovascular Diseases and Risks, 1990-2022.
J Am Coll Cardiol
December 2023
Department of Health Metrics Sciences, Institute for Health Metrics and Evaluation, School of Medicine, University of Washington, Seattle, Washington, USA; Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA. Electronic address:
Interval and Consecutive Round Breast Cancer after Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Standard 2D Digital Mammography in BreastScreen Norway.
Radiology
February 2020
From the Departments of Radiology (T.H., H.B.) and Research (K.K.S.), Vestre Viken Hospital Trust, Drammen, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway (T.H.); Cancer Registry of Norway, Oslo, Norway (Å.S.H., S.H.); Department of Diagnostic Radiology, Department of Translational Medicine, Lund University, Malmö, Sweden (K.L.); Institute for Biomedical Engineering, Zurich, Switzerland (K.L.); Departments of Radiology (J.L.A.) and Pathology (P. Suhrke), Vestfold Hospital Trust, Tønsberg, Norway; Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway (S.H.B.B., P. Skaane); and Department of Life Sciences and Health, Faculty of Health Science, Oslo Metropolitan University, PO 5313 Majorstuen, 0304, Oslo, Norway (S.H.).
Background Screening that includes digital breast tomosynthesis (DBT) with two-dimensional (2D) synthetic mammography (SM) or standard 2D digital mammography (DM) results in detection of more breast cancers than does screening with DM alone. A decrease in interval breast cancer rates is anticipated but is not reported. Purpose To compare rates and characteristics of interval breast cancer in women screened with DBT and SM versus those screened with DM alone and screen-detected breast cancer at consecutive screenings with DM.
View Article and Find Full Text PDFApplication of whole-exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia.
Br J Haematol
October 2017
Centre for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Rare inherited bleeding disorders (IBD) are a common cause of bleeding tendency. To ensure a correct diagnosis, specialized laboratory analyses are necessary. This study reports the results of an upfront diagnostic strategy using targeted whole exome sequencing.
View Article and Find Full Text PDFDigital breast tomosynthesis (3D-mammography) screening: A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials.
Breast
April 2016
Department of Radiology, Oslo University Hospital Ullevaal, University of Oslo, Norway.
This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trials that performed standard (2D) digital mammography (DM) and tomosynthesis (3D-mammography) in the same screening participants. Exemplar cases from four trials highlight common themes of relevance to screening practice including: the type of lesions frequently made more conspicuous or perceptible by tomosynthesis (spiculated masses, and architectural distortions); the histologic findings (both TP and FP) of tomosynthesis-only detection; and the need to extend breast work-up protocols (additional imaging including ultrasound and MRI, and tomosynthesis-guided biopsy) if tomosynthesis is adopted for primary screening.
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