1 results match your criteria: "Department of Surgery and Pathology at the University of Michigan Medical Center[Affiliation]"
Prevention of ventilator-induced lung injury with partial liquid ventilation.
J Pediatr Surg
September 2001
Department of Surgery and Pathology at the University of Michigan Medical Center, Ann Arbor, MI, USA.
Background/purpose: Pulmonary injury from mechanical ventilation has been attributed to application of excess alveolar pressure (barotrauma) or volume (volutrauma). The authors questioned whether partial liquid ventilation (gas ventilation of the perfluorocarbon filled lung, PLV) would reduce ventilator-induced lung injury.
Methods: A tracheostomy tube and carotid artery catheter were placed in anesthetized Sprague-Dawley rats (500 +/- 50 g).