1 results match your criteria: "Department of Surgery and North Carolina Jaycee Burn Center[Affiliation]"
Toll-like receptor 2 and 4 ligation results in complex altered cytokine profiles early and late after burn injury.
J Trauma
April 2008
Department of Surgery and North Carolina Jaycee Burn Center, Chapel Hill, North Carolina, USA.
Background: Toll-like receptors (TLR) 2 and TLR4 expressed on innate immune cells are important mediators of the immune response to pathogens. In this study, we hypothesized that burn injury results in altered cytokine secretion profiles after TLR2 or TLR4 ligation that is associated with altered TLR expression on innate immune cells.
Methods: Female C56BL/6 mice were subjected to 20% full thickness burn or sham injury.