6 results match your criteria: "Department of Surgery Yokosuka Kyosai Hospital Yokosuka Japan.[Affiliation]"

Article Synopsis
  • The study aimed to test whether adjuvant chemotherapy for stage III colon cancer could be effectively shortened from the conventional 6 months to 3 months using the SOX regimen (S-1 and oxaliplatin).
  • In a randomized phase II trial, patients received either 3 months or 6 months of SOX treatment, with the primary goal of measuring 3-year disease-free survival (DFS).
  • Results showed that the 3-year DFS rates were similar for both groups (75% for 6 months and 76.9% for 3 months), indicating that shortening the treatment did not significantly improve outcomes, and the primary endpoint was not met.
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Aim: There have been no reports of searching for metastases to lymph nodes along the accessory middle colic artery (aMCA). The aim of this study was to investigate the metastasis rate of the aMCA for splenic flexural colon cancer.

Methods: Patients with histologically proven colon carcinoma located in the splenic flexure, clinically diagnosed as stage I-III were eligible for this study.

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Background: Real-world outcomes of nivolumab treatment for gastric cancer and associated prognostic factors remain unclear; the present study aimed to evaluate both items.

Methods: A total of 278 consecutive patients treated with nivolumab for gastric cancer during 2017-2019 were enrolled in this multi-institutional retrospective cohort study. The impact of laboratory findings, immune-related adverse events (irAEs), and clinicopathological factors on long-term survival was evaluated using the Cox proportional hazards model.

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Article Synopsis
  • The study investigated the impact of continuing vs. discontinuing antiplatelet therapy during the perioperative period for colorectal cancer patients undergoing laparoscopic surgery.
  • A total of 214 patients were analyzed, with no significant differences observed in blood loss, transfusion needs, or postoperative complications between those who continued antiplatelet therapy and those who stopped it before surgery.
  • The findings suggest that maintaining antiplatelet therapy may be preferable for cardiovascular and cerebrovascular safety during laparoscopic colorectal cancer surgery, especially given the cases of stroke in the discontinuation group.
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Aim: The present study clarified the effect on the health-related quality of life and patient satisfaction of single-incision laparoscopic colectomy compared with multiport laparoscopic colectomy for colorectal cancer.

Methods: We conducted a multicenter, randomized, control trial comparing single-incision and multiport laparoscopic colectomy for colon cancer. We performed a pre-planned secondary analysis of health-related quality of life and patient satisfaction data of 200 patients.

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Background: Surgical site infection (SSI) is a common morbidity in patients undergoing colorectal surgery, and the focus of previous studies has primarily been on incisional SSI. Most reports thus far have focused on open surgery rather than on laparoscopic colorectal surgery (Lap CR). Therefore, the aim of the present study was to identify the risk factors for incisional SSI in patients undergoing elective Lap CR.

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