11 results match your criteria: "Department of Surgery National Defense Medical College Tokorozawa Japan.[Affiliation]"
Risk factors for serious postoperative complications following gastrectomy in super-elderly patients ≥85-years-old with gastric cancer: A National Clinical Database study in Japan.
Ann Gastroenterol Surg
January 2025
The Japanese Society of Gastroenterological Surgery Tokyo Japan.
Article Synopsis
- The study evaluates the safety and feasibility of gastrectomy in patients aged 85 and older with gastric cancer.
- It analyzed data from over 10,000 patients who underwent distal or total gastrectomy to identify risks for serious postoperative complications.
- Key risk factors included physical health indicators like body mass index, daily living activities, and past medical history, highlighting the need for careful assessment beyond just tumor characteristics.
Pivotal articles that had been published between 2022 and 2023 on surgical and perioperative adjuvant treatments for locally advanced colorectal cancer (CRC) were reviewed. This review focuses on new evidence in the following areas: optimization of surgical procedures for colon cancer, including the optimal length of bowel resection and use of the no-touch isolation technique; minimally invasive surgery for rectal cancer, such as laparoscopic transanal total mesorectal excision and robotic surgery; neoadjuvant treatments for rectal cancer, including total neoadjuvant therapy; neoadjuvant chemotherapy for colon cancer; and postoperative adjuvant chemotherapy for Stage II and III colon cancer. Although the current understanding may not enable perfect decision-making for patients and medical professionals, ongoing advancements are expected to result in more effective personalized treatment plans, ultimately improving the prognosis and quality of life of patients.
View Article and Find Full Text PDFBackground: Due to the coronavirus disease 2019 (COVID-19) pandemic, cancer screening, diagnosis, and treatment have changed. This study aimed to investigate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection prior to gastroenterological cancer surgeries on postoperative complications using data from a nationwide database in Japan.
Methods: Data on patients who underwent surgery for cancer including esophageal, gastric, colon, rectal, liver, and pancreatic cancer between July 1, 2019, and September 300, 2022, from real-world sources in Japan were analyzed.
Peritoneal lavage cytology in patients with curative resection for stage II and III colorectal cancer: A multi-institutional prospective study.
Ann Gastroenterol Surg
September 2024
Division of Molecular and Diagnostic Pathology Niigata University, Graduate School of Medical and Dental Sciences Niigata Japan.
Article Synopsis
- Study aimed to assess the impact of intraoperative lavage cytology on patient outcomes in colorectal cancer surgeries, specifically focusing on stages II-III.
- Out of 1378 patients, lavage revealed positive cytology in only 54 cases, with significant differences in 5-year relapse-free survival and overall survival rates between positive and negative cytology in stage II patients.
- The findings indicate that negative cytology correlates with better outcomes and highlights the effectiveness of lavage cytology in predicting peritoneal recurrence in these cancer patients.
Efficacy of lateral lymph node dissection for local control of rectal cancer: A multicenter study.
Ann Gastroenterol Surg
July 2024
Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Science Niigata University Niigata Japan.
Article Synopsis
- * A total of 189 patients who underwent total mesorectal excision and LLND were included, and data on local recurrence (LR) and lateral lymph node recurrence (LLNR) were analyzed after matching similar patient characteristics.
- * While 39 patients had pathological LLNM, the analysis showed similar rates of LR and LLNR in both groups after balancing their characteristics, suggesting LLND can provide comparable local control regardless of LLNM presence.
A proposed new Japanese classification of synchronous peritoneal metastases from colorectal cancer: A multi-institutional, prospective, observational study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Ann Gastroenterol Surg
September 2023
Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Aim: To establish a new Japanese classification of synchronous peritoneal metastases from colorectal cancer.
Methods: This multi-institutional, prospective, observational study enrolled patients who underwent surgery for colorectal cancer with synchronous peritoneal metastases. Overall survival rates were compared according to the various models using objective indicators.
Aim: There have been no reports of searching for metastases to lymph nodes along the accessory middle colic artery (aMCA). The aim of this study was to investigate the metastasis rate of the aMCA for splenic flexural colon cancer.
Methods: Patients with histologically proven colon carcinoma located in the splenic flexure, clinically diagnosed as stage I-III were eligible for this study.
Background: Damage control resuscitation improves patient outcomes after severe hemorrhage and coagulopathy. However, effective hemostasis methods for these critical situations are lacking.
Objective: We evaluated the hemostatic efficacy of fibrinogen γ-chain (HHLGGAKQAGDV, H12)-coated, adenosine-diphosphate (ADP)-encapsulated liposomes (H12-[ADP]-liposomes) in thrombocytopenic rabbits with hemorrhagic shock.
Aim: Neuroendocrine tumors (NETs) are one of the subtypes of neuroendocrine neoplasms and are defined as epithelial neoplasms with predominant neuroendocrine differentiation. The aim of this study was to clarify the clinicopathological characteristics of colorectal NETs through a nationwide retrospective study in Japan.
Methods: This multicenter retrospective cohort study of NETs in Japan was conducted by the study group of the Japanese Society for Cancer of the Colon and Rectum.
Aim: The prognostic value of the stage III subclassification system based on the Japanese Classification of Colorectal, Appendiceal, and Anal Carcinoma has not yet been clarified. This study aimed to develop a modified system with optimal risk stratification and compare its performance with the current staging systems.
Methods: Clinicopathological data from 6855 patients with stage III colorectal cancers who underwent D3 dissection were collected from a nationwide multicenter database.
Aim: Impact of several immune-inflammatory markers on long-term outcome has been reported in various malignancies. The aim of the present study was to evaluate through a meta-analysis the oncological outcome of immune-inflammatory markers, such as neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and C-reactive protein to albumin ratio (CAR) in esophageal cancer.
Methods: A systematic electronic search for relevant studies was carried out in PubMed, Cochrane library, Embase, and Google scholar.