Distribution of opioid analgesics by community racial/ethnic and socioeconomic profiles, 2011-2021.

Rapid declines in opioid analgesics dispensed in American communities since 2011 raise concerns about inadequate access to effective pain management among patients for whom opioid therapies are appropriate, especially for those living in racial/ethnic minority and socioeconomically deprived communities. Using 2011 to 2021 national data from the Automated Reports and Consolidated Ordering System and generalized linear models, this study examined quarterly per capita distribution of oxycodone, hydrocodone, and morphine (in oral morphine milligram equivalents [MMEs]) by communities' racial/ethnic and socioeconomic profiles. Communities (defined by 3-digit-zip codes areas) were classified as "majority White" (≥50% self-reported non-Hispanic White population) vs "majority non-White.

Schizophrenia and retention in HIV care among adults insured through Medicaid in the United States: a population-based retrospective cohort study.

Background: People with schizophrenia spectrum disorders are at elevated risk of HIV, and people with both HIV and schizophrenia are at elevated risk of death compared to individuals with either diagnosis alone. Limited research has assessed the HIV care cascade, and in particular retention in care, among people with HIV (PWH) and schizophrenia in the U.S.

Regulation and Compliance in Telemedicine: Viewpoint.

The US COVID-19 Public Health Emergency ended on May 11, 2023. Lawmakers and regulators extended some flexibilities while they deliberate effective long-term telemedicine policy. Here, we discuss critical challenges in telemedicine compliance and regulation grounded in scholarly literature and current events.

Child Maltreatment Characteristics and Adult Physical Multimorbidity in Germany.

Importance: Associations between child maltreatment (CM) and health have been studied broadly, but most studies focus on multiplicity (number of experienced subtypes of CM). Studies assessing multiple CM characteristics are scarce, partly due to methodological challenges, and were mostly conducted in patient samples.

Objective: To determine the importance of CM characteristics in association with physical multimorbidity in adulthood for women and men in a German representative sample.

The perceptual primacy of feeling: Affectless visual machines explain a majority of variance in human visually evoked affect.

Looking at the world often involves not just seeing things, but feeling things. Modern feedforward machine vision systems that learn to perceive the world in the absence of active physiology, deliberative thought, or any form of feedback that resembles human affective experience offer tools to demystify the relationship between seeing and feeling, and to assess how much of visually evoked affective experiences may be a straightforward function of representation learning over natural image statistics. In this work, we deploy a diverse sample of 180 state-of-the-art deep neural network models trained only on canonical computer vision tasks to predict human ratings of arousal, valence, and beauty for images from multiple categories (objects, faces, landscapes, art) across two datasets.

Early intervention in eating disorders: introducing the chronopathogram.

Eating disorders (EDs) pose significant challenges to mental and physical health, particularly among adolescents and young adults, with the COVID-19 pandemic exacerbating risk factors. Despite advancements in psychosocial and pharmacological treatments, improvements remain limited. Early intervention in EDs, inspired by the model developed for psychosis, emphasizes the importance of timely identification and treatment initiation to improve prognosis.

Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe.

Purpose: To systematically review qualitative studies on outcomes, needs, experiences, preferences, concerns and health-related quality of life (HRQoL) of people surviving cancer in Europe in the last decade.

Methods: Protocol registered ( https://www.crd.

Challenges when Combining Expertise to Provide Integrated Care for Youth At-Risk and Their Family: A Qualitative Study.

The needs of youth at-risk and their families, facing multiple problems and serious mental health issues, exceed the expertise and possibilities of a single stakeholder (professional, organization, municipality). These youngsters require care in which the expertise of different professionals and organizations is integrated. However, combining various types of expertise to provide integrated care to youth at-risk is challenging.

Judaism, Women's Health and COVID-19.

This issue commences with a review of the top 100 most cited papers in the Journal of Religion and Health. This is followed by Part 2 of a series examining Judaism and health related research, which is subsequently followed by an extensive collection of research specifically connected to women's health. Finally, research continues to present the unique and ongoing effects of COVID-19.

Feasibility and effects of cognitive training on cognition and psychosocial function in Huntington's disease: a randomised pilot trial.

Background: Huntington's disease (HD) is a rare neurodegenerative disease that causes progressive cognitive, physical, and psychiatric symptoms. Computerised cognitive training (CCT) is a novel intervention that aims to improve and maintain cognitive functions through repeated practice. The effects of CCT have yet to be established in HD.

Acute effects of psilocybin on attention and executive functioning in healthy volunteers: a systematic review and multilevel meta-analysis.

Rationale: Psilocybin shows promise for treating neuropsychiatric disorders. However, insight into its acute effects on cognition is lacking. Given the significant role of executive functions in daily life and treatment efficacy, it is crucial to evaluate how psilocybin influences these cognitive domains.

After the storm, the calm never came: Hurricane Maria-related stressors and PTSD symptoms among Puerto Rican youth.

Objective: Youth may develop posttraumatic stress disorder (PTSD) following a hurricane. Triaging of mental health services is crucial to effectively deliver trauma-focused interventions following natural disasters. Given the increased likelihood of hurricanes due to the current climate crisis, this study sought to examine the dose-response effect between hurricane-related stressors and PTSD, identify a cumulative stressor cutoff score based on the number of hurricane-related stressors experienced, and identify important individual hurricane-related stressors in explaining PTSD symptoms among youth.

Posttraumatic resilience and growth: A network analysis of character strengths among sexual assault survivors.

Objective: Defined as dispositional qualities that elevate well-being, character strengths such as love and kindness can be developed and enhanced to improve quality of life. Yet, little is known how specific strengths are associated with posttrauma mental health. The present study explored their concurrent associations with posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG) in a sample of 405 women sexual assault survivors.

Determinants of stigma against help-seeking in schools and help-seeking behaviors of Asian American and Latinx youth experiencing internalizing problems.

Objectives: This study examined individual and school factors related to stigma against seeking mental health support among Asian American and Latinx youth and tested whether stigma moderated the link between internalizing symptoms and help-seeking behaviors across different sources of support.

Methods: Data were drawn from a cross-sectional, routine school-based mental health needs assessment. The sample included 1,371 Asian American and 801 Latinx students in Grades 4-12 ( = 8.

The family's role in mental health care: Perceptions of Bay Area Muslims.

This qualitative study examines perceptions of Muslims living in the San Francisco Bay Area, California, United States, regarding the family's role in mental health help-seeking and well-being. This study employed a community-based participatory research approach through content analysis of three focus group ( = 37) discussions conducted with the help of a community advisory board comprised San Francisco Bay Area Muslim community members. Four main themes were generated.

Outcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial.

Background: Chronic limb-threatening ischemia (CLTI) in patients with chronic kidney disease (CKD) has a high risk of poor outcomes. We aimed to compare the outcomes of lower extremity revascularization in patients with CLTI stratified by CKD severity in patients enrolled in the prospective, randomized Best Endovascular vs Best Surgical Therapy in Patients with CLTI (BEST-CLI) trial.

Methods: The BEST-CLI trial dataset was queried to categorize patients into three groups according to CKD stage.

Novel Pharmacologic Treatments of Female Sexual Dysfunction.

This review evaluates pharmacologic treatments for female sexual dysfunction (FSD), focusing on hypoactive sexual desire disorder (HSDD). We provide clinically relevant applications for Food and Drug Administration (FDA)-approved medications (flibanserin and bremelanotide) and investigational therapies (Lorexys and testosterone combinations). Detailed study outcomes, safety profiles, and clinical strategies guide clinicians in appropriate diagnosis, patient selection, expectation setting, side effect management, and patient education, improving treatment outcomes and patient satisfaction.

Victimisation in other- and self-directed violence as a function of ethnicity and primary diagnosis among inpatients with serious mental illness.

Background: Among individuals with serious mental illness (SMI), victimisation has been found to increase the risk of engaging in other- and self-directed violence. However, rates of victimisation within this population have been found to vary by ethnic group and primary diagnosis.

Aims: This study primarily aimed to examine the relationship between victimisation and other- and self-directed violence among a sample of inpatients with SMI during the first 3 months of admission.

LncRNA Is Upregulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3.

Aging leads to cognitive decline and increased risk of neurodegenerative diseases. While molecular changes in central nervous system (CNS) cells contribute to this decline, the mechanisms are not fully understood. Long non-coding RNAs (lncRNAs) are key regulators of cellular functions.

Autoantibodies, Oxidative Stress, and Nutritional State in Anorexia Nervosa.

: Anorexia nervosa (AN) is a complex psychiatric disorder characterized by an extreme fear of gaining weight, leading to severe calorie restriction and weight loss. Beyond its psychiatric challenges, AN has significant physical consequences affecting multiple organ systems. Recent research has increasingly focused on the interplay between autoantibodies, oxidative stress, and nutritional state in this condition.

Genetic Predisposition to Hippocampal Atrophy and Risk of Amnestic Mild Cognitive Impairment and Alzheimer's Dementia.

Background: There is a paucity of evidence on the association between genetic propensity for hippocampal atrophy with cognitive outcomes. Therefore, we examined the relationship of the polygenic risk score for hippocampal atrophy (PRShp) with the incidence of amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD) as well as the rates of cognitive decline.

Methods: Participants were drawn from the population-based HELIAD cohort.

Impairment of the Functional Status and Decrease in Albumin in Frail Older People After a COVID-19 Outbreak: A Descriptive Study in a Long-Term Care Facility in Chile.

Frailty is a common condition among older individuals and is associated with increased vulnerability to adverse health outcomes. The COVID-19 pandemic further highlighted the impact of viral infections on frail populations. The present work aimed to determine frailty, functional and cognitive status, and clinical analysis of older persons in a long-term care facility in Chile, before and following the outbreak of COVID-19.

Two Clinically Implementable Digital PCR Assessments of DNA Methylation for Diagnosing Heavy Alcohol Consumption.

Background: Heavy alcohol consumption (HAC) has a profound adverse effect on human health. Unfortunately, there is a relative lack of tools that are easily implementable in clinical settings and that can be used to supplement self-reporting in the diagnosis and management of HAC. In part, this paucity is due to limitations of currently available biological measures and a mismatch between available biological measures and the needs of clinicians managing HAC.