1 results match your criteria: "Department of Physiology Northwestern University Feinberg School of Medicine Chicago Illinois USA.[Affiliation]"
Introduction: Amyloid-beta oligomers (AβOs) accumulate in Alzheimer's disease and may instigate neuronal pathology and cognitive impairment. We examined the ability of a new probe for molecular magnetic resonance imaging (MRI) to detect AβOs in vivo, and we tested the behavioral impact of AβOs injected in rabbits, a species with an amino acid sequence that is nearly identical to the human sequence.
Methods: Intracerebroventricular (ICV) injection with stabilized AβOs was performed.