1 results match your criteria: "Department of Physical Therapy Health Sciences University of Hokkaido Kanazawa Ishikari-Tobetsu[Affiliation]"
p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice.
J Cachexia Sarcopenia Muscle
May 2016
Department of Physical Therapy Health Sciences University of Hokkaido Kanazawa Ishikari-Tobetsu, Hokkaido Japan.
Aim: We investigated the pathway of autophagy signaling linked to sarcopenia of mice.
Methods: Young adult (3-month) and aged (24- month) C57BL/6J mice were used. Using real-time PCR, Western blotting, and immunohistochemical microscopy, we evaluated the amounts of p62/SQSTM1, LC3, and Beclin-1 in the quadriceps muscle change with aging in mice.