5 results match your criteria: "Department of Pharmacy Showa University Koto Toyosu Hospital Tokyo Japan.[Affiliation]"
Key Clinical Message: An 86-year-old geriatric patient with sepsis presented cibenzoline-induced hypoglycaemia, although within the boundary range of cibenzoline blood concentration.
Abstract: An 86-year-old geriatric patient taking cibenzoline for ametropic hypertrophic cardiac tendinopathy was admitted to our hospital for the treatment of sepsis. Upon admission, blood cibenzoline levels of 400.
Identifying causative medications for agranulocytosis: A case report of an older adult with cerebral infarction.
Clin Case Rep
February 2024
Department of Hospital Pharmaceutics, School of Pharmacy Showa University Tokyo Japan.
Article Synopsis
- Identifying drugs causing adverse events in critically ill patients is challenging due to multiple medications involved, as illustrated in the case of a 93-year-old man with cerebrovascular issues.
- The patient developed agranulocytosis after being treated with several medications, prompting the clinical team to prioritize medication adjustments.
- Ultimately, clopidogrel was determined to be the likely culprit after monitoring and discontinuing other suspected drugs, leading to an improvement in the patient's condition.
Key Clinical Message: EDTA-dependent pseudothrombocytopenia as well as myelosuppression should be suspected when thrombocytopenia occurs in patients with autoimmune disease during chemotherapy.
Abstract: A patient with pancreatic cancer and ulcerative colitis developed transient ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia with exacerbation of ulcerative colitis during chemotherapy. Unfortunately, pseudothrombocytopenia could not be immediately detected because thrombocytopenia was masked by a reasonable time course of adverse events associated with chemotherapy and ulcerative colitis recurrence.
A super-geriatric patient with gastrostomy underwent life-threatening prothrombin time-international normalized ratio prolongation by warfarin following fasting and antibiotic therapy.
Clin Case Rep
September 2023
Department of Hospital Pharmaceutics, School of Pharmacy Showa University Tokyo Japan.
Key Clinical Message: A 97-year-old woman with gastrostomy had a drastic enhancement for PT-INR after starting antibiotic therapy. Possible causes include (1) vitamin K deficiency due to fasting and (2) a combination of warfarin and antibiotics.
Abstract: Geriatric and Asian-descent patients are more sensitive to the effects of warfarin, a key anticoagulant drug.
Gemcitabine induce thrombocytopenia and thrombocytosis as toxicity. In this report, we show detailed time-course for platelet fluctuation. Our case emphasis attention to monitor see-saw-like toxicity on platelet count.
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