3 results match your criteria: "Department of Pediatrics at Northwestern University Feinberg School of Medicine[Affiliation]"
Incidence, Predictors, and Impact of Postoperative Acute Kidney Injury Following Fontan Conversion Surgery in Young Adult Fontan Survivors.
Semin Thorac Cardiovasc Surg
June 2022
Division of Cardiology, Ann & Robert H Lurie Children's Hospital of Chicago, Department of Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Article Synopsis
- Acute kidney injury (AKI) is a frequent complication after single ventricle congenital heart surgeries, particularly following Fontan conversion (FC), with 45% of patients experiencing AKI post-surgery.
- Risk factors for severe AKI (AKI≥2) include older age, multiple previous surgeries, and higher preoperative right atrial pressure.
- Patients with severe AKI face longer recovery times, increased need for dialysis, and lower mid-term heart-transplant-free survival rates compared to those with milder AKI.
Despite an ongoing need for pediatric research, low study enrollment may impede study completion, particularly in critical care. We conducted a prospective cross-sectional survey and chart review study to assess parent experiences with research in a pediatric intensive care unit (PICU). Of the 80 parents who completed the study survey, 54% were approached to participate in a research study in the PICU, and 93% agreed to participate.
View Article and Find Full Text PDFAugmented Renal Clearance Using Population-Based Pharmacokinetic Modeling in Critically Ill Pediatric Patients.
Pediatr Crit Care Med
September 2017
1University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences and School of Medicine, La Jolla, CA. 2Miller Children's Hospital, Long Beach, CA. 3Department of Pharmacy Practice, Midwestern University, Chicago College of Pharmacy, Downers Grove, IL. 4Division of Critical Care Medicine in the Department of Pediatrics at Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, IL. 5The Division of Infectious Diseases, University of San Diego, School of Medicine and Rady Children's Hospital of San Diego, La Jolla, CA. 6Department of Pharmacy, King Hussein Cancer Center, Amman, Jordan.
Objectives: The objectives of this study were to: 1) evaluate the prevalence of augmented renal clearance in critically ill pediatric patients using vancomycin clearance; 2) derive the pharmacokinetic model that best describes vancomycin clearance in critically ill pediatric patients; and 3) correlate vancomycin clearance with creatinine clearance estimated by modified Schwartz or Cockcroft-Gault.
Design: Retrospective, two-center, cohort study from 2003 to 2016.
Setting: Clinical drug monitoring services in the PICUs at two tertiary care, teaching hospitals.