The study aimed to assess the effectiveness of puerarin in reducing lung injuries caused by Streptozotocin (STZ)-induced diabetes in rats.
The researchers observed significant increases in nitric oxide (NO) and malondialdehyde (MDA) levels, along with decreased superoxide dismutase (SOD) activity in the lungs of diabetic rats, while puerarin treatment mitigated these effects.
Microscopic analyses showed that diabetes caused structural damage in lung tissues, but puerarin treatment appeared to restore some of that damage, suggesting its potential protective role against diabetes-induced lung injury.