5 results match your criteria: "Department of Otolaryngology-Head and Neck Surgery Thomas Jefferson University Philadelphia Pennsylvania USA.[Affiliation]"
J Extracell Biol
November 2024
Departments of Pharmacology Physiology, and Cancer Biology, Thomas Jefferson University Philadelphia Pennsylvania USA.
The translation of pre-clinical anti-cancer therapies to regulatory approval has been promising, but slower than hoped. While innovative and effective treatments continue to achieve or seek approval, setbacks are often attributed to a lack of efficacy, failure to achieve clinical endpoints, and dose-limiting toxicities. Successful efforts have been characterized by the development of therapeutics designed to specifically deliver optimal and effective dosing to tumour cells while minimizing off-target toxicity.
View Article and Find Full Text PDFWorld J Otorhinolaryngol Head Neck Surg
June 2023
Objectives: Otolaryngology-specific requirements were piloted to minimize applicant and program burdens. We investigated the impact of introducing and then removing these requirements on Match outcomes.
Methods: 2014-2021 National Resident Matching Program® data were examined.
Laryngoscope Investig Otolaryngol
February 2023
Objectives: Patients are increasingly relying on YouTube for health information. We objectively evaluated the quality and comprehensiveness of sialendoscopy YouTube videos available to patients. We further investigated the relationship between video content and video popularity.
View Article and Find Full Text PDFLaryngoscope Investig Otolaryngol
February 2023
Objectives: We previously reported that >50% of postoperative opioids prescribed at our institution went unused for common otolaryngologic procedures. Based on these findings, we instituted multimodal, evidence-based guidelines for postoperative pain management. In the second part of our multiphasic study, we evaluated the effects of these guidelines on (1) quantity of unused opioids, (2) patient satisfaction, and (3) institutional perceptions toward the opioid epidemic and prescribing guidelines.
View Article and Find Full Text PDFUnlabelled: Button batteries (BB) are found in common household items and can lead to significant morbidity and mortality in the pediatric population when ingested. BBs are made of various chemistries and have a unique size and shape that yield significant injury when lodged in the pediatric esophagus. BBs create a local tissue pH environment of 10 to 13 and can induce liquefactive necrosis at the negative pole.
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