64 results match your criteria: "Department of Oral Health and Clinical Science[Affiliation]"
Adv Exp Med Biol
October 2024
Department of Oral Health and Clinical Science, Division of Special Needs Dentistry and Orofacial Pain, Tokyo Dental College, Tokyo, Japan.
Gum chewing is used in orofacial therapy to improve oral functions, such as a patient's chewing ability, bite force, tongue pressure, and lip closure strength. However, its effects on masseter muscle oxygen dynamics and muscle activity may vary with the hardness and features of the gum base. Therefore, when considering gum chewing for therapeutic purposes, it is essential to select gum of an appropriate hardness.
View Article and Find Full Text PDFAdv Exp Med Biol
October 2024
Department of Oral Health and Clinical Science, Division of Special Needs Dentistry and Orofacial Pain, Tokyo Dental College, Tokyo, Japan.
This study aimed to clarify the effect of 1 month of gum chewing (GCh) training on masseter muscle oxygen dynamics and determine its effectiveness in improving muscle endurance and fatigue. A total of 16 healthy adult subjects were included in this study. The subjects were randomly assigned to two groups: control and training groups (eight subjects each).
View Article and Find Full Text PDFAdv Exp Med Biol
October 2024
Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.
The purpose of this study was to examine the effects on prefrontal cortex (PFC) activity of listening to pleasant sounds (PS) while walking, gum chewing (GCh), or performing the dual task of walking and gum chewing at the same time (walking + GCh). A total of 11 healthy adult male volunteers participated in the study (mean age: 29.54 ± 3.
View Article and Find Full Text PDFMol Pain
August 2024
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Phantom tooth pain (PTP) is one type of non-odontogenic neuropathic toothache, which rarely occurs after appropriate pulpectomy or tooth extraction. The cause of PTP is unknown. We investigated pain-related genetic factors that are associated with PTP.
View Article and Find Full Text PDFEur J Dent
October 2024
Department of Biomaterials Science and TCBC, Institute of Dentistry, University of Turku, Turku, Finland.
Objectives: The aim of the study was to evaluate the mechanical properties and impact absorption capacity of prototype materials comprising ethylene vinyl acetate (EVA) of different hardness reinforced using different amounts of glass fibers (GFs), considering a buffer space.
Materials And Methods: Six prototype materials were made by adding E-GFs (5 and 10 wt%) to EVA with vinyl acetate (VA) contents of 9.4 wt% ("hard" or HA) and 27.
Dysphagia
December 2024
Department of Oral Health and Clinical Science, Division of Dysphagia Rehabilitation, Tokyo Dental College, 2-9-18 Kanda-Misakicho, Chiyoda-ku, Tokyo, 101-0061, Japan.
Aging affects the tongue and suprahyoid muscles, causing dysphagia and undernutrition. We hypothesized that tongue function would affect submental superficial layer hardness. Tongue movements during water retention between the tongue and palate are the same as those required during bolus formation, involving internal and external tongue muscle movement.
View Article and Find Full Text PDFInt J Mol Sci
December 2023
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Patients with chronic pain are affected psychologically and socially. There are also individual differences in treatment efficacy. Insufficient research has been conducted on genetic polymorphisms that are related to individual differences in the susceptibility to chronic pain.
View Article and Find Full Text PDFBiomedicines
August 2023
Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
G protein-coupled receptors in trigeminal ganglion (TG) neurons are often associated with sensory mechanisms, including nociception. We have previously reported the expression of P2Y receptors, which are G protein-coupled receptors, in TG cells. Activating P2Y receptors decreased the intracellular free Ca concentration ([Ca]).
View Article and Find Full Text PDFPain Res Manag
September 2023
Division of Special Needs Dentistry and Orofacial Pain, Department of Oral Health and Clinical Science, Tokyo Dental College, Tokyo 101-0061, Japan.
The inferior alveolar nerve block (IANB) is an established technique with a success rate of 60-80%; however, large errors have been reported among operators. Some dentists do not prefer to use IANB because of the risk of complications. Nevertheless, it is a useful technique for pain control, and a secure IANB offers significant benefits to operators and patients.
View Article and Find Full Text PDFDysphagia occurs in various diseases and constitutes a major concern in patients with psychiatric disorders. The Mann Assessment of Swallowing Ability (MASA) comprises 24 clinical parameters designed to identify swallowing disorders. One item in MASA, the "gag reflex", involves an unpleasant stimulus, which means that it is often omitted when the test is administered.
View Article and Find Full Text PDFMol Pain
November 2023
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Phantom tooth pain (PTP) is a rare and specific neuropathic pain that occurs after pulpectomy and tooth extraction, but its cause is not understood. We hypothesized that there is a genetic contribution to PTP. The present study focused on the gene, which encodes the α1C subunit of the Ca1.
View Article and Find Full Text PDFInt J Mol Sci
April 2023
Department of Pain and Palliative Medicine, The University of Tokyo Hospital, Hongo 7-3-1, Bunkyoku, Tokyo 113-8655, Japan.
Autotaxin, encoded by the gene, is a known key element of neuropathic pain; however, its involvement in nociceptive pain processing remains unclear. We explored the associations between postoperative pain intensity, 24-h postoperative opioid dose requirements, and 93 -gene single-nucleotide polymorphisms (SNPs) in 362 healthy patients who underwent cosmetic surgery using the dominant, recessive, and genotypic models. Next, we validated the associations between relevant SNPs on the one hand and pain intensity and daily opioid dosages on the other in 89 patients with cancer-related pain.
View Article and Find Full Text PDFInt J Mol Sci
April 2023
Department of Anatomy, Tokyo Dental College, 2-9-18 Kandamisaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
Myostatin (Myo) is known to suppress skeletal muscle growth, and was recently reported to control tendon homeostasis. The purpose of the present study was to investigate the regulatory involvement of Myo in the myotendinous junction (MTJ) in vivo and in vitro. After Achilles tendon injury in mice, we identified unexpected cell accumulation on the tendon side of the MTJ.
View Article and Find Full Text PDFDent Traumatol
August 2023
Division of Special Needs Dentistry and Orofacial Pain, Department of Oral Health and Clinical Science Dentistry, Tokyo Dental College, Chiyoda, Japan.
Background/aim: During sports activities, teeth-related contact can cause injury to both ally and opponent players, which can lead to potential infections and aesthetic problems. However, the extent of such injuries remains unclear. This study aimed to clarify the frequency and situation of head injuries caused by teeth (HICBT) occurring under the supervision of schools in Japan.
View Article and Find Full Text PDFInt J Mol Sci
January 2023
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Chronic pain is reportedly associated with the transient receptor potential canonical 3 () gene. The present study examined the genetic associations between the single-nucleotide polymorphisms (SNPs) of the gene and chronic pain. The genomic samples from 194 patients underwent linkage disequilibrium (LD) analyses of 29 SNPs within and around the vicinity of the gene.
View Article and Find Full Text PDFAdv Exp Med Biol
December 2022
Department of Oral Health and Clinical Science, Division of Special Needs Dentistry and Orofacial Pain, Tokyo Dental College, Tokyo, Japan.
The purpose of this study was to clarify the effects of jaw-clenching intensity on masseter muscle oxygen dynamics during clenching and recovery and masseter muscle fatigue using the spatially resolved method of near-infrared spectroscopy. Pulse rate, mean power frequency from electromyography in the masseter and visual analogue scale for masseter fatigue were also examined as related items. The 25% and 50% maximum voluntary contractions were determined using electromyography before the experiment and used as visual feedback on the screen.
View Article and Find Full Text PDFDent Traumatol
April 2023
Department of Biomaterials Science and TCBC Institute of Dentistry, University of Turku, Turku, Finland.
Background/aims: A light-cured intermediate material is useful for fabricating a hard insert and a buffer space mouthguard (H&SMG). However, it requires improvement in its mechanical properties and shock-absorbing capacity. The aim of this study was to evaluate the mechanical properties of two prototype light-cured intermediate materials reinforced with glass fibers, and the impact absorption capacity and durability of H&SMGs made with the prototype intermediate materials.
View Article and Find Full Text PDFEur J Dent
July 2023
Division of Special Needs Dentistry and Orofacial Pain, Department of Oral Health and Clinical Science Dentistry, Tokyo Dental College, Tokyo, Japan.
Objective: Mouthguards can prevent and reduce orofacial sports traumas, which occur to the players themselves. However, the effect of mouthguards on skin damage has not been clarified. The present study's purpose was to examine whether the mouthguard can reduce or prevent skin damage caused by teeth (including the difference in mouthguard thickness).
View Article and Find Full Text PDFOral hypofunction is the stage at which recovery can be expected with proper diagnosis, management, and motivation before oral dysfunction occurs. The knowledge and attitude toward oral function can influence the maintenance and improvement of oral function. However, whether middle-aged and older adults with declining oral function have knowledge of their oral function and how this knowledge and their attitude affect their oral function are unclear.
View Article and Find Full Text PDFJ Pain Res
May 2022
Department of Oral and Maxillofacial Surgery, Tokyo Dental College, Tokyo, Japan.
Background: Refractory chronic pain in the orofacial region involves central sensitization (CS). However, not all chronic pain patients exhibit CS. An objective assessment of CS may be useful for pain management.
View Article and Find Full Text PDFPharmaceutics
March 2022
Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.
Rehabil Res Pract
April 2022
Department of Oral Health and Clinical Science, Division of Special Needs Dentistry and Orofacial Pain, Tokyo Dental College, Chiyoda-ku, Tokyo 101-0061, Japan.
Maintaining oral hygiene is an important yet often neglected aspect of rehabilitation medicine. Our visiting dental team, which provides dental treatments and swallowing rehabilitation, partnered with a medical hospital that had no dental department and began visiting and treating inpatients at this hospital. This study is aimed at evaluating the effects of dysphagia rehabilitation, and this was jointly conducted by medical and dental hospitals.
View Article and Find Full Text PDFMol Pain
October 2022
Addictive Substance Project, 13931Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Phantom tooth pain (PTP) is a rare and specific neuropathic pain that occurs after pulpectomy and tooth extraction, but its cause is not understood. We hypothesized that there is a genetic contribution to PTP. We focused on solute carrier family 17 member 9 (SLC17A9)/vesicular nucleotide transporter (VNUT) and purinergic receptor P2Y12 (P2RY12), both of which have been associated with neuropathic pain and pain transduction signaling in the trigeminal ganglion in rodents.
View Article and Find Full Text PDFJ Dent Anesth Pain Med
October 2021
Division of Special Needs Dentistry and Orofacial Pain, Department of Oral Health and Clinical Science, Tokyo Dental College, Tokyo, Japan.
Background: Neurovascular compression (NVC) is a well-known cause of trigeminal neuralgia (TN). However, patients with idiopathic TN (ITN) do not have evidence of NVC on magnetic resonance imaging (MRI), and other patients may remain asymptomatic despite evidence of NVC on MRI. This suggests that there may be additional risk factors for TN development other than NVC.
View Article and Find Full Text PDFJ Oral Biosci
December 2021
Department of Anatomy, Tokyo Dental College, 2-9-18 Kanda-misakicho, Tokyo, 101-0061, Japan; Tokyo Dental College Research Branding Project, 2-9-18 Kanda-misakicho, Tokyo, 101-0061, Japan. Electronic address:
Objectives: Temporomandibular joint osteoarthritis (TMJ-OA) causes degenerative changes in TMJ tissues. The inter-tissue crosstalk that exacerbates illness and organic changes in bone secondary to TMJ-OA potentially affects the muscles; therefore, patients with a muscular disease might also suffer from bone disease. However, knowledge gaps exist concerning muscle pathology at the onset of TMJ-OA.
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