Ultrasonography and color Doppler-based triage for adnexal masses to provide the most appropriate surgical approach.

Objective: This study was undertaken to identify whether ultrasonography with color Doppler can identify and triage the patients with adnexal masses to the most appropriate surgical approach.

Study Design: Four hundred fifty-three pelvic masses were included in the study and underwent ultrasonography before surgical treatment for adnexal masses. Masses that showed a typical benign pattern at B-mode ultrasonography (very low risk of malignancy) were treated by conventional laparoscopy without further evaluation.

Hyperinsulinemia and uterine perfusion in patients with polycystic ovary syndrome.

Objective: To determine whether hyperinsulinemia has a negative effect on uterine blood supply in patients with polycystic ovary syndrome (PCOS).

Methods: Sixty-three patients with normal body mass index were included prospectively in the study: 48 had clinical and hormonal features of PCOS and 15 were normo-ovulatory. All patients underwent Doppler flow measurement of the uterine artery, and determination of serum concentrations of luteinizing hormone, follicle stimulating hormone, prolactin, estradiol, androgens, insulin and C-peptide during the early follicular phase of the menstrual cycle.

The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome.

Objective: To evaluate whether, by blocking androgen action, flutamide can decrease and normalize vascular resistance in the uterine artery in patients with polycystic ovary syndrome (PCOS).

Design: Prospective and controlled study.

Setting: Endocrinological Centre of the Department of Obstetrics and Gynecology of the University of Cagliari, Italy.