2 results match your criteria: "Department of Nursing Hung-Kuang University[Affiliation]"
This study investigated the effects of methanol extract (MEMO) on baroreceptor reflex sensitivity (BRS) in the hypercholesterolemic rabbits and the involved molecular mechanisms. Male New Zealand white rabbits were randomly divided into Control (normal diet), Cholesterol (0.5% w/w cholesterol diet), and Magnolia groups (0.
View Article and Find Full Text PDFHypoxia/Reoxygenation induces nitric oxide and TNF-alpha release from cultured microglia but not astrocytes of the rat.
Chin J Physiol
June 2007
Basic Medical Science, Department of Nursing Hung-Kuang University, Taichung, Taiwan, Republic of China.
Article Synopsis
- Hypoxia/reoxygenation (H/R) leads to cell injury in neurons and activates glial cells in the central nervous system, resulting in neuroinflammation due to the release of substances like nitric oxide (NO) and tumor necrosis factor alpha (TNF-alpha).
- In studies, it was found that while microglial cells struggle to survive prolonged hypoxia (>12 hours), astrocytes maintain high viability (95%) but do not release significant amounts of NO or TNF-alpha.
- Following a 24-hour hypoxia, reoxygenation for up to five days increases NO production significantly, with TNF-alpha release occurring prior to NO in mixed glial cultures, highlighting the differing responses and roles