4 results match your criteria: "Department of Neurology RWTH Aachen University Aachen Germany.[Affiliation]"
Peri-lead edema (PLE) after deep brain stimulation may mimic brain infection on magnetic resonance imaging (MRI). We present a case of symptomatic PLE with annular contrast enhancement on MRI suggestive of an infectious cause. We show that careful clinical evaluation and laboratory testing, in addition to neuroimaging, are essential to guide treatment and to avoid unnecessary interventions in PLE cases with a favorable spontaneous course.
View Article and Find Full Text PDFCognitive profiles of patients with mild cognitive impairment due to Alzheimer's versus Parkinson's disease defined using a base rate approach: Implications for neuropsychological assessments.
Alzheimers Dement (Amst)
September 2021
Department of Medical Psychology Neuropsychology & Gender Studies; Center for Neuropsychological Diagnostics and Intervention (CeNDI) Faculty of Medicine and University Hospital Cologne, University of Cologne Cologne Germany.
Article Synopsis
- - The study focuses on comparing cognitive profiles of patients with mild cognitive impairment related to Alzheimer's disease (AD-MCI) and Parkinson's disease (PD-MCI), noting that large studies on this topic are limited.
- - Data from two large cohort studies were analyzed using a common diagnostic approach, revealing that AD-MCI patients performed worse on memory and language tests, while PD-MCI patients struggled more with executive tasks involving set-shifting.
- - The results indicate that a specific neuropsychological test battery can effectively differentiate between AD-MCI and PD-MCI, suggesting that clinical assessments should encompass a wide range of cognitive areas to identify potential changes.
Background: Physical activity has shown a positive impact on aging and neurodegeneration and represents a possible treatment option in cognitive decline. However, its underlying mechanisms and influences on brain pathology remain unclear. Dementia-MOVE (Multi-Objective Validation of Exercise) is a randomized-controlled pilot trial, including 50 patients with amnestic cognitive impairment associated with Alzheimer's pathology, aiming to analyze the effect of physical activity and fitness on disease progression.
View Article and Find Full Text PDFCognition in Friedreich's ataxia: a behavioral and multimodal imaging study.
Ann Clin Transl Neurol
August 2016
Objective: Friedreich's ataxia (FRDA) is a spinocerebellar degenerative disorder, in which cognitive deficits are sparsely explored. In this behavioral and multimodal magnetic resonance imaging (MRI) study, we investigated the neurocognitive profile and cortico-cerebellar dysfunctions underlying executive functioning in individuals with FRDA.
Methods: 22 FRDA patients and 22 controls were clinically and neuropsychologically examined.