3 results match your criteria: "Department of Neurology Lanzhou University Second Hospital Lanzhou Gansu China. Electronic address: tougao13893647595@163.com.[Affiliation]"
Ischemic stroke can cause damage to neurons, resulting in neurological dysfunction. The main treatments in the acute phase include intravenous thrombolysis, endovascular stent-assisted vascular thrombectomy and antiplatelet therapy. Due to the limitations of the time window and the risk of early intracranial hemorrhage, finding active treatment plans is crucial for improving therapy.
View Article and Find Full Text PDFAstrogliosis and glial scar in ischemic stroke - focused on mechanism and treatment.
Exp Neurol
December 2024
Department of Neurology, Lanzhou University Second Hospital, Lanzhou 730030, Gansu, China. Electronic address:
Ischemic stroke is a kind of neurological dysfunction caused by cerebral ischemia. Astrocytes, as the most abundant type of glial cells in the central nervous system, are activated into reactive astrocytes after cerebral ischemia, and this process involves the activation or change of a series of cell surface receptors, ion channels and ion transporters, GTPases, signaling pathways, and so on. The role of reactive astrocytes in the development of ischemic stroke is time-dependent.
View Article and Find Full Text PDFResearch progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia.
Neurochem Int
January 2024
Department of Neurology, Lanzhou University Second Hospital, Lanzhou, Gansu, 730030, China. Electronic address:
Article Synopsis
- * Activated microglia can take on two forms: M1, which promotes inflammation, and M2, which helps reduce it; their balance is crucial for recovery post-stroke.
- * The article emphasizes how different microglial functions, such as autophagy and programmed cell death (like pyroptosis), can either help or harm brain recovery, and it discusses the gaps in current research on this topic.