9 results match your criteria: "Department of Neurology Hospital Universitario Ramón y Cajal Madrid Spain.[Affiliation]"

Background: Idiopathic normal pressure hydrocephalus (iNPH) is characterized by the classic clinical triad of gait, cognitive, and urinary dysfunction, albeit incomplete in a relevant proportion of patients. The clinical findings and evolution of these symptoms have been variably defined in the literature.

Objectives: To evaluate how the phenomenology has been defined, assessed, and reported, we performed a critical review of the existing literature discussing the phenomenology of iNPH.

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Article Synopsis
  • Dopamine replacement therapy is crucial for managing motor and nonmotor symptoms in Parkinson's disease, but treatment adjustments become necessary as the disease progresses.
  • The study aimed to validate the OPTIMIPARK questionnaire, which assesses patient symptoms, to aid clinicians in making treatment decisions for those on levodopa.
  • Results showed that the OPTIMIPARK score led to more patients needing treatment changes compared to standard evaluations, suggesting it could be a more effective tool for determining therapeutic needs in Parkinson's patients.
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Background: Clinical diagnosis of atypical parkinsonisms may be challenging. The eye-of-the-tiger sign on brain MRI, typical of neurodegeneration with brain iron accumulation, has been anecdotally observed in cases clinically diagnosed as atypical parkinsonisms.

Objectives: To show how clinical syndromes and even neuroimaging sometimes may lead the neurologist to a misunderstanding, just as to emphasize the important role of pathology to establish the final diagnosis in these cases.

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Background: Parkinson's disease (PD) patients, especially those on dopamine agonists (DA), are at risk of impulse control disorders (ICD). Little attention has been paid to the influence of environmental factors.

Cases: Retrospective analysis of consecutive PD patients seen in our outpatient Movement Disorders Clinic during 2 months (September-November 2020) to explore the frequency of ICD during the preceding 2-month lockdown period, and comparison with an equivalent control group (September-November 2019).

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Background: Impulse control disorders (ICDs) have an increased frequency in patients with Parkinson's disease (PD), mainly because of treatment with dopamine agonists (DA). Factors related with the country of origin (culture, economy, healthcare politics) may impact phenomenology.

Objectives: To explore phenomenology of ICDs depending on the country.

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Introduction: Response to drug withdrawal in patients with suspected drug-induced parkinsonism (DIP) is of prognostic and therapeutic importance, but cannot be predicted solely on clinical information. The aim of this study was to validate SN hyperechogenicity (SN+) assessed by transcranial sonography as a predictor of response to drug withdrawal in this group of patients.

Methods: Patients were diagnosed according to previously published criteria and prospectively included in the study.

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