20 results match your criteria: "Department of Neurology All India Institute of Medical Sciences New Delhi India.[Affiliation]"
Continuous Subcutaneous Infusion Delivery of Apomorphine in Parkinson's Disease: A Systematic Review.
Mov Disord Clin Pract
September 2023
Movement Disorders Section Fleni, CONICET Buenos Aires Argentina.
Background: Continuous subcutaneous apomorphine infusion (CSAI) is one of the advanced therapies for Parkinson's disease (PD).
Methods: A systematic review of all published articles in English on CSAI for PD till January 30, 2022 was conducted.
Results: A total of 82 articles met the search criteria.
Article Synopsis
- Neuropathic Tremor (NT) can occur in patients recovering from Guillain-Barré Syndrome (GBS), characterized by a postural/kinetic tremor of the upper extremities.
- NT in this context features a fine, fast, slightly jerky tremor with frequencies between 8 to 10 Hz, often accompanied by dystonic posturing and overflow movements.
- Electrophysiological evaluations suggest that NT involves a central oscillator mechanism, potentially linked to cerebellar dysfunction due to impaired sensorimotor feedback during recovery from GBS.
Article Synopsis
- The study explores how Parkinson's disease affects various aspects of social cognition in Indian patients, highlighting impairments in understanding social situations compared to healthy volunteers.
- Using the SOCRATIS tool, researchers assessed theory of mind, attributional biases, and social cue perception in 52 PD patients and 31 healthy volunteers.
- Results showed that PD patients struggled more with social cognition and had a tendency to blame external factors for negative events, but these deficits did not correlate with their overall quality of life.
Background: Hereditary Spastic Paraparesis HSP) are a group of genetically inherited disorders, clinically and genetically heterogenous and characterized by degeneration of corticospinal tracts, manifesting with progressive spasticity and lower limbs weakness. Most HSPs have an autosomal dominant inheritance. "Ear of the Lynx" sign describes the characteristic abnormality in the forceps minor region of the corpus callosum (CC) on MRI brain.
View Article and Find Full Text PDFBackground: Coronavirus disease 2019 (COVID-19) causes abnormalities in the hemostatic system, collectively known as COVID-associated coagulopathy. The dynamics of clot formation are best discerned by whole-blood viscoelastic tests, such as thromboelastography (TEG). We aimed to assess the various abnormalities seen on TEG and explored the predictors of outcomes in these patients.
View Article and Find Full Text PDFChronic pancreatitis (CP) is an irreversible disease with increased oxidative stress. The therapeutic role of antioxidants for pain reduction in CP is debatable. A systematic review of articles in PubMed and Embase until February 2020 was performed.
View Article and Find Full Text PDFBackground: Anticholinergic drugs are associated with significant cognitive and other adverse events in older adults, including those with Parkinson's disease (PD). Anticholinergic effects are considered lesser in younger individuals and the burden and outcomes in younger patients with PD are unknown.
Objectives: To determine the cumulative anticholinergic burden in a cohort of younger of patients with PD and to correlate the same with cognitive impairment and freezing of gait (FOG).
Management practices for West syndrome in South Asia: A survey study and meta-analysis.
Epilepsia Open
September 2020
Objectives: Considering the dearth of literature on West syndrome (WS) from South Asian countries, this study aimed to evaluate the management practices in South Asia by an online survey and meta-analysis.
Methods: An online questionnaire was sent to 223 pediatric neurologists/pediatricians in India, Pakistan, Myanmar, Sri Lanka, Bhutan, Nepal, and Bangladesh. Their responses were evaluated and supplemented by a meta-analysis.
Background: Autonomic dysfunction forms the diagnostic cornerstone in MSA. Data are limited on autonomic dysfunction differences between the two subtypes, MSA-C and MSA-P.
Objectives: To assess autonomic dysfunction in MSA subtypes and Parkinson's disease (PD) and compare it to healthy controls.
Background: Hemi masticatory spasm (HMS) is a rare movement disorder affecting muscles of mastication attributed to dysfunction of motor branch of trigeminal nerve and is characterized by painful spasm of masticatory muscles. Microvascular compression leading to focal demyelination of motor branch of trigeminal nerve is the most speculated on mechanism of HMS. Treatment options range from medical to surgical approaches, but botulinm toxin (BTX) has now become the preferred treatment.
View Article and Find Full Text PDFObjective: EpiNet was established to encourage epilepsy research. EpiNet is used for multicenter cohort studies and investigator-led trials. Physicians must be accredited to recruit patients into trials.
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