2 results match your criteria: "Department of Neurological Surgery at Northwestern University Feinberg School of Medicine[Affiliation]"
Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.
Brain Behav Immun Health
July 2024
Department of Neurological Surgery at Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
Article Synopsis
- Increased age is a significant unfavorable factor for glioblastoma (GBM) prognosis, but the interplay between patient age, comorbidities, and medications on survival has not been thoroughly studied.
- The study analyzed electronic health records of 565 GBM patients to evaluate the impact of age and various health conditions on survival and established potential targets for future research.
- Key findings revealed that younger patients had poorer outcomes related to movement disabilities and mental health issues, while older patients showed worse prognosis linked to epilepsy; both age groups benefited from Temozolomide and older patients from ACE-inhibitor prescriptions.
A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer.
Brain Behav Immun Health
May 2022
Department of Neurological Surgery at Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Background: Older adults ≥65 years of age represent the majority of new cancer diagnoses and are vulnerable to developing depression-like symptoms. Evaluation and management of depression in older cancer patients is underappreciated despite its high prevalence and impact on health-related quality of life. Although antidepressants are the primary pharmacologics used to treat depressive-like symptoms, the efficacy and overall benefit(s) are not well-characterized in older adult patients with cancer.
View Article and Find Full Text PDF