2 results match your criteria: "Department of Molecular and Cellular Biochemistry University of Kentucky Lexington Kentucky USA.[Affiliation]"
Article Synopsis
- Traumatic brain injury (TBI) causes damage that leads to increased blood clotting, which can result in serious complications like coagulopathy and delayed thrombosis.
- The study aimed to investigate the role of tissue factor (TF) in promoting thrombin generation following TBI by using controlled injury models and examining blood samples at different times post-injury.
- Results showed that TF levels and thrombin generation were significantly higher in one injury model (CCI) compared to control, indicating that TF plays a crucial role in the coagulation response after TBI, with variations based on injury type and severity.
Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome.
Alzheimers Dement (Amst)
October 2020
Department of Pathology and Laboratory Medicine University of California, Irvine Irvine California USA.
Introduction: Microglial cells play an important role in the development of Alzheimer's disease (AD). People with Down syndrome (DS) inevitably develop AD neuropathology (DSAD) by 40 years of age. We characterized the distribution of different microglial phenotypes in the brains of people with DS and DSAD.
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