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Introduction: The coronavirus (COVID-19) pandemic has led to as well as exacerbated mental health disorders, leading to increased use of psychotropic medications. Co-administration of COVID-19 and psychotropic medications may result in drug-drug interactions (DDIs), that may compromise both the safety and efficacy of both medications.

Areas Covered: This review provides an update of the current evidence on DDIs between COVID-19 and psychotropic medications.

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