6 results match your criteria: "Department of Medicine University of Massachusetts Chan Medical School Worcester Massachusetts USA.[Affiliation]"

Introduction: Alzheimer's disease (AD) is a heterogeneous disorder characterized by complex underlying neuropathology that is not fully understood. This study aimed to identify cognitive progression subtypes and examine their correlation with clinical outcomes.

Methods: Participants of this study were recruited from the Framingham Heart Study.

View Article and Find Full Text PDF

Toward a common standard for data and specimen provenance in life sciences.

Learn Health Syst

January 2024

Interdisciplinary Bank of Biomaterials and Data Würzburg (ibdw) Würzburg Germany.

Article Synopsis
  • The importance of openly sharing and reusing specimens and data in life sciences research is highlighted, as it directly affects the quality of findings and knowledge.
  • Accurate documentation of pre-analytical conditions, analytical procedures, and data processing is crucial to validate research results, but current information on sample and data provenance is often inadequate.
  • The publication discusses a standardization effort aimed at creating reliable machine-actionable documentation for data lineage and specimens, inviting experts from biotechnology and biomedical fields to contribute to this initiative.
View Article and Find Full Text PDF

Objectives: Pandemic disruptions to interviews and away rotations led applicants to rely on alternative sources of information about residency programs. We sought to compare program characteristics important to emergency medicine (EM)-bound applicants from before and after the pandemic. We also investigated the sources of information pandemic impacted applicants used during residency recruitment.

View Article and Find Full Text PDF

Objective: Obesity increases morbidity and mortality from Coronavirus disease 2019 (COVID-19). This study characterized inpatient complications among patients with obesity and COVID-19-including myocardial infarction, renal failure requiring dialysis, stroke, secondary bacterial infection, and venous thromboembolism-and identified factors associated with developing at least one inpatient complication at a safety-net hospital with a diverse cohort.

Methods: A retrospective review was performed of all patients admitted for ≥3 days with COVID-19 between 16 March 2020, and 8 April 2020.

View Article and Find Full Text PDF

Previously viewed as a culture contaminant, can cause infection following neurosurgical intervention. Its role in brain abscess in the immunocompetent, surgically naïve population has been infrequently reported. Herein, we describe an immunocompetent 55-year-old man with no risk factors found to have a thalamic abscess with intraventricular rupture.

View Article and Find Full Text PDF