3 results match your criteria: "Department of Medicine Institute of Microbiology.[Affiliation]"
Potential Microbiological Effects of Higher Dosing of Echinocandins.
Clin Infect Dis
December 2015
Division of Pediatric Infectious Diseases, Department of Pediatrics.
The antifungal "paradoxical effect" has been described as the reversal of growth inhibition at high doses of echinocandins, most usually caspofungin. This microbiological effect appears to be a cellular compensatory response to cell wall damage, resulting in alteration of cell wall content and structure as well as fungal morphology and growth. In vitro studies demonstrate this reproducible effect in a certain percentage of fungal isolates, but animal model and clinical studies are less consistent.
View Article and Find Full Text PDFInfluence of IFNL3/4 polymorphisms on the incidence of cytomegalovirus infection after solid-organ transplantation.
J Infect Dis
March 2015
Infectious Diseases Service, Department of Medicine.
Background: Polymorphisms in IFNL3 and IFNL4, the genes encoding interferon λ3 and interferon λ4, respectively, have been associated with reduced hepatitis C virus clearance. We explored the role of such polymorphisms on the incidence of cytomegalovirus (CMV) infection in solid-organ transplant recipients.
Methods: White patients participating in the Swiss Transplant Cohort Study in 2008-2011 were included.