5 results match your criteria: "Department of Medicine Columbia University New York NY USA.[Affiliation]"

Article Synopsis
  • * The strategies simulated include usual care, intensive care targeting lower blood pressure, and team-based care, indicating varying levels of effectiveness in reducing CVD events.
  • * While intensive care could prevent up to 138,100 cardiovascular events annually, it is also associated with a significant increase in serious treatment-related adverse events, raising concerns about safety.
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Article Synopsis
  • The REDUCE-IT USA trial found that icosapent ethyl (IPE) significantly reduced cardiovascular events by 31% and 36% over approximately 4.9 years.
  • An analysis of the cost-effectiveness of IPE compared to standard care (SC) showed that IPE was less expensive and provided better health outcomes, particularly at a daily cost of $4.59.
  • Overall, IPE is recommended for U.S. patients similar to those in the trial, as it remains cost-effective even at a higher daily cost of $11.48.
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Osteoporosis causes fragile bone, and bone microstructural quality is a critical determinant of bone strength and fracture risk. This study pursues technical validation of novel CT-based methods for assessment of peripheral bone microstructure together with a human pilot study examining relationships between bone microstructure and vertebral fractures in smokers. To examine the accuracy and reproducibility of the methods, repeat ultra-high-resolution (UHR) CT and micro-CT scans of cadaveric ankle specimens were acquired.

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The purpose of this study is to explore the impact of body weight change following intentional weight loss on incident fracture and bone mineral density (BMD) in overweight and obese adults with diabetes. A total of 1885 individuals with type 2 diabetes (baseline age: 58.5 ± 6.

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