The study investigated an outbreak of rifampicin-resistant ribotype 027 (RT 027) fecal isolates in a Polish hospital from late 2017 to early 2018 using multilocus variable tandem repeat analysis (MLVA).
Twenty-nine fecal isolates were analyzed, revealing that all strains contained specific toxin genes and had varying antibiotic resistance profiles, including significant resistance to imipenem (97%) and rifampicin (45%).
The findings indicated a transmission outbreak of multidrug-resistant RT 027, likely due to poor hygiene and spore presence in the hospital, highlighting the need for further research into the resistance mechanisms.