1 results match your criteria: "Department of Internal Medicine. University of Campinas (Unicamp)[Affiliation]"
Physical exercise elicits UPR in the skeletal muscle: The role of c-Jun N-terminal kinase.
Mol Metab
December 2023
Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences (FCA), University of Campinas (Unicamp), Limeira, Brazil; Faculty of Medical Sciences, Department of Internal Medicine. University of Campinas (Unicamp), Campinas, São Paulo, Brazil. Electronic address:
Objective: The mitochondrial unfolded protein response (UPR) is an adaptive cellular response to stress to ensure mitochondrial proteostasis and function. Here we explore the capacity of physical exercise to induce UPR in the skeletal muscle.
Methods: Therefore, we combined mouse models of exercise (swimming and treadmill running), pharmacological intervention, and bioinformatics analyses.