1 results match your criteria: "Department of Internal Medicine at the University of Iowa in Iowa City[Affiliation]"

Management of resistant prolactinomas.

Nat Clin Pract Endocrinol Metab

October 2006

Division of Endocrinology and Metabolism, Department of Internal Medicine at the University of Iowa in Iowa City, IA 52242, USA.

Resistance to dopamine agonists occurs in a subset of patients with prolactin-secreting pituitary tumors. The resistance is mediated by loss of pituitary D2 receptors and occurs in both microadenomas and macroadenomas. Cabergoline is the most effective dopamine agonist and tumors that do not respond to bromocriptine or quinagolide frequently respond to cabergoline.

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