1 results match your criteria: "Department of Internal Medicine University of Iowa Health Care Iowa City Iowa USA.[Affiliation]"
Pegcetacoplan in paroxysmal nocturnal hemoglobinuria: A systematic review on efficacy and safety.
Res Pract Thromb Haemost
July 2022
Department of Hematology, Oncology, and Blood & Marrow Transplantation, Department of Internal Medicine University of Iowa Health Care Iowa City Iowa USA.
Introduction: Pegcetacoplan, a pegylated penta-decapeptide, targets complement C3 to control both intravascular and extravascular hemolysis. This systematic review aims to study the efficacy and safety of pegcetacoplan in paroxysmal nocturnal hemoglobinuria (PNH).
Methods: We performed a comprehensive and systematic literature search for all studies on PubMed, Google Scholar, Cochrane Library, and clinicaltrials.