21 results match your criteria: "Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.[Affiliation]"
Article Synopsis
- The Japanese Catheter Ablation (J-AB) registry, launched in August 2017, is a nationwide voluntary study led by the Japanese Heart Rhythm Society focused on collecting data about catheter ablation procedures.
- In January 2022, the registry's data collection system shifted from REDCap to the Fountayn system to improve data management.
- By the end of 2022, the registry compiled data from 90,042 procedures across 614 hospitals, highlighting the types of arrhythmias, outcomes, and complications, with participants averaging 66.7 years old and 65.9% being male.
Infective endocarditis due to nasal septal perforation during home oxygen therapy.
Respirol Case Rep
October 2024
Division of Respiratory Diseases, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- A 64-year-old man on home oxygen therapy developed infective endocarditis (IE) linked to a nasal septal perforation, causing respiratory issues.
- Methicillin-sensitive Staphylococcus aureus (MSSA) was found repeatedly in blood cultures and also isolated from the patient's nasal cavity.
- Despite treatment with antibiotics, he later suffered from aspiration pneumonia and died, highlighting the importance of proper nasal care to prevent severe infections during home oxygen therapy.
Introduction: Transplant renal vein thrombosis is a serious post-transplant complication. We report a case in which a thrombus was found in the transplant renal vein and rescued the transplanted kidney utilizing interventional radiology.
Case Presentation: A 56-year-old woman underwent ABO-compatible living donor renal transplantation due to impaired renal function caused by IgA nephropathy.
Article Synopsis
- Previous studies on the effectiveness of cryoballoon ablation (CBA) versus radiofrequency ablation (RFA) for treating atrial fibrillation have yielded mixed results, highlighting the need for a cost comparison between the two methods.
- A systematic review and meta-analysis showed that while CBA had a slightly lower rate of AF recurrence compared to RFA, the difference was not statistically significant, and the cost analysis revealed RFA was more affordable.
- The study concludes that both treatments offer similar outcomes for AF recurrence, but RFA may be the more cost-effective option, suggesting treatment choices should consider both clinical and cost factors.
The association between hyperuricemia and atrial fibrillation recurrence after catheter ablation.
J Arrhythm
June 2024
Division of Cardiology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Background: Hyperuricemia (HU) has been reported to be associated with a high incidence of atrial fibrillation (AF). However, the relationship between HUA and recurrent AF after catheter ablation (CA) is unclear.
Methods: Four hundred consecutive AF patients (paroxysmal/persistent AF [PAF/PsAF]: 200/200) who underwent the initial CA were retrospectively enrolled.
A novel combined C-reactive protein-albumin ratio and modified albumin-bilirubin score can predict long-term outcomes in patients with hepatocellular carcinoma after hepatic resection.
Ann Gastroenterol Surg
January 2024
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- - The study examines how the combined score of C-reactive protein and albumin ratio (CAR) and modified albumin-bilirubin (mALBI) affects prognosis in patients with hepatocellular carcinoma (HCC) after liver surgery.
- - Conducted on 214 patients who had liver resection for HCC between 2008 and 2018, the research categorizes patients based on their CAR and mALBI scores to assess their disease-free and overall survival rates.
- - Results show that a higher CAR-mALBI score correlates with lower survival rates, highlighting its potential as a significant prognostic tool for evaluating both the liver's function and the patient's inflammatory state in HCC management.
The Japanese Catheter Ablation (J-AB) registry, started in August 2017, is a voluntary, nationwide, multicenter, prospective, observational registry, performed by the Japanese Heart Rhythm Society (JHRS) in collaboration with the National Cerebral and Cardiovascular Center using a Research Electronic Data Capture system. The purpose of this registry is to collect the details of target arrhythmias, the ablation procedures, including the type of target arrhythmias, outcomes, and acute complications in the real-world settings. During the year of 2021, we have collected a total of 89 609 procedures (mean age of 66.
View Article and Find Full Text PDFArticle Synopsis
- The study examined how the combination of Child-Pugh class B/C cirrhosis, sarcopenia, and severe vitamin D deficiency affects the survival prognosis of cirrhosis patients.
- The researchers evaluated 104 patients and found that those with both high-risk cirrhosis and either sarcopenia or severe vitamin D deficiency had significantly lower survival rates compared to those without these complications.
- The findings suggest that assessing nutritional issues like sarcopenia and vitamin D levels is crucial for understanding and improving the prognosis of patients with cirrhosis.
Background And Aim: Patients with gastroesophageal reflux disease (GERD) frequently also have functional dyspepsia (FD) symptoms, which impair their quality of life. However, the magnitude and characteristics of the effects of each symptom on daily life have been unclarified. Using multiple regression analysis, we aimed to clarify these questions.
View Article and Find Full Text PDFDay-to-Day Blood Pressure Variability and Risk of Incident Chronic Kidney Disease in a General Japanese Population.
J Am Heart Assoc
October 2022
Department of Epidemiology and Public Health, Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Background Several longitudinal studies have reported that higher visit-to-visit blood pressure variability is associated with greater risk for developing chronic kidney disease. However, no population-based studies have investigated the association between day-to-day home blood pressure variability and incident chronic kidney disease. Methods and Results A total of 2342 Japanese community-dwelling residents aged ≥40 years without chronic kidney disease at baseline were followed up by annual health examinations for 10 years.
View Article and Find Full Text PDFSafety and efficacy of pentazocine-midazolam combination for pain and anxiety relief in radiofrequency ablation therapy for hepatocellular carcinoma.
JGH Open
August 2022
Division of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Background And Aim: Radiofrequency ablation (RFA) therapy is frequently used as first-line treatment for small hepatocellular carcinoma (HCC). RFA is often associated with pain; however, no definitive solution has been established for its relief. We retrospectively analyzed the safety and efficacy of the combination of pentazocine and midazolam to relieve pain experienced by HCC patients undergoing RFA.
View Article and Find Full Text PDFImpact of qualitative endoscopic ultrasonography on fatty pancreas at a referral medical center.
JGH Open
January 2022
Division of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- The study assessed the clinical implications of pancreatic steatosis, or fat accumulation in the pancreas, using endoscopic ultrasonography (EUS) amid rising metabolic syndrome concerns.
- It involved 243 patients divided into four groups, analyzing the relationship between the echogenicity (brightness on imaging) of the pancreas versus control organs, determining key cut-off ratios.
- Findings indicated significant correlations between factors like sex, alcohol use, and fatty pancreas, highlighting that ectopic fat in the pancreas may signal serious conditions such as pancreatic cancer, particularly in high-risk individuals.
Endoscopic ultrasound-guided fine-needle biopsy histology with a 22-gauge Franseen needle and fine-needle aspiration liquid-based cytology with a conventional 25-gauge needle provide comparable diagnostic accuracy in solid pancreatic lesions.
JGH Open
September 2021
Division of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- This study aimed to compare the diagnostic effectiveness of two biopsy methods: a 22-gauge Franseen needle (22G-FNB-H) for histology and a 25-gauge needle (25G-FNA-LBC) for liquid-based cytology in patients with solid pancreatic lesions.
- The research involved 46 patients and found a high agreement rate of 93.5% for identifying malignancy between both techniques, with no significant difference in their diagnostic abilities.
- The results suggest that both methods have comparable accuracy, allowing for flexibility in choosing a technique based on the endoscopist's skill and the specific case.
Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk.
J Extracell Vesicles
August 2021
Article Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a serious lung disease characterized by progressive fibrosis and poor patient outcomes, linked to abnormal gene expression involved in lung healing.*
- Human bronchial epithelial cell-derived extracellular vesicles (HBEC EVs) have been shown to inhibit the harmful effects of TGF-β, which leads to myofibroblast differentiation and cellular aging, more effectively than mesenchymal stem cell-derived EVs.*
- The beneficial effects of HBEC EVs are driven by their microRNA cargo, which reduces key WNT signaling pathways and demonstrates potential for becoming a novel treatment strategy for IPF by decreasing lung fibrosis.*
Article Synopsis
- This study explored sarcopenia (muscle loss) in patients with alcoholic liver cirrhosis (ALC) and examined the impact of heavy alcohol consumption on this condition.
- Of the 181 patients analyzed, 35.4% had ALC, and those patients were younger with a lower prevalence of sarcopenia compared to patients with non-ALC, despite having more severe liver disease.
- The findings suggest that older age is a significant factor linked to sarcopenia in ALC patients, while heavy alcohol consumption did not appear to significantly contribute to its development.
The clinical manifestations of COVID-19 vary broadly, ranging from asymptomatic infection to acute respiratory failure and death. But the predictive biomarkers for characterizing the variability are still lacking. Since emerging evidence indicates that extracellular vesicles (EVs) and extracellular RNAs (exRNAs) are functionally involved in a number of pathological processes, we hypothesize that these extracellular components may be key determinants and/or predictors of COVID-19 severity.
View Article and Find Full Text PDFBackground: To analyze the type of ablation procedure, acute outcomes, and complications related to catheter ablation in Japan during the year of 2018.
Method: The Japanese Catheter Ablation (J-AB) registry is a voluntary, nationwide, multicenter, prospective, observational registry, performed by the Japanese Heart Rhythm Society (JHRS) in collaboration with the National Cerebral and Cardiovascular Center using a Research Electronic Data Capture system. The procedural outcome and complications during hospitalizations were collected.
Article Synopsis
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Background: Catheter ablation has become a popular interventional treatment for cardiac tachyarrhythmias and the number has been on the rise year by year. However, little is known about its efficacy and safety in the real-world settings.
Method: Japanese Catheter Ablation (J-AB) Registry is a nationwide, multicenter, observational registry, performed by Japanese Heart Rhythm Society (JHRS), collaborated with National Cerebral and Cardiovascular Center.
Pleuritis associated with primary Sjogren syndrome.
Respirol Case Rep
February 2018
Division of Respiratory Medicine, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
We herein present a case of a 71-year-old woman with primary Sjogren's syndrome (SjS), who developed bilateral pleural effusion and ground glass opacity during treatment with low-dose prednisolone. The pleural effusion and bronchoalveolar lavage fluid revealed elevation of lymphocytes. Thoracoscopic pleural biopsy showed infiltration of lymphocytes with no evidence of other diseases, confirming SjS-related pleuritis.
View Article and Find Full Text PDFSuccessful control of a case of severe insulin allergy with liraglutide.
J Diabetes Investig
January 2013
Division of Diabetes, Metabolism and Endocrinology Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Article Synopsis
- A 72-year-old woman experienced frequent low and high blood sugar episodes due to an allergy to insulin.
- She was diagnosed with type B insulin resistance syndrome and had antibodies against insulin.
- After treatment with steroids improved her condition, liraglutide was added, effectively managing her blood sugar levels without causing allergic reactions.