2 results match your criteria: "Department of Internal Medicine II-Division of Cardiology Medical University of Vienna Vienna Austria.[Affiliation]"
J Am Heart Assoc
January 2024
J Am Heart Assoc
June 2020
Background Neprilysin is a transmembrane endopeptidase involved in the breakdown of a variety of vasoactive peptides and serves as a therapeutic target in heart failure with reduced ejection fraction (HFrEF). This study aimed to investigate the relationship of circulating neprilysin with neurohumoral activation and the impact of plasma neprilysin activity on prognosis in HFrEF. Methods and Results A total of 369 chronic HFrEF patients were enrolled prospectively.
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