4 results match your criteria: "Department of Internal Medicine (Cardiology Division) of the Washington Hospital Center[Affiliation]"
Background: Catheter-based local drug delivery at the site of stent implantation has been proposed to reduce in-stent restenosis. We examined whether local delivery itself may cause additional vessel wall injury and negate the potential benefit of local drug delivery in a porcine coronary in-stent restenosis model.
Methods: Pigs were randomly assigned to no local delivery (controls, n = 10) or local saline infusion (5 ml) using commercially available catheters (n = 39; Dispatch catheter, Microporous Infusion catheter, and InfusaSleeve) prior to oversized (stent:artery ratio 1.
Coron Artery Dis
May 1997
Department of Internal Medicine (Cardiology Division) of the Washington Hospital Center, District of Columbia, USA.
Background: In-stent restenosis is primarily due to neointimal hyperplasia. Results from recent nonrandomized studies suggest that local delivery of heparin or urokinase to the site of angioplasty or stenting results in a lower rate of restenosis.
Objective: To determine whether local delivery of heparin or urokinase reduces in-stent restenosis.
Am Heart J
July 1996
Department of Internal Medicine (Cardiology Division) of the Washington Hospital Center, Washington, DC 20010, USA.