5,460 results match your criteria: "Department of Hyperbaric Medicine; Kayseri City Hospital[Affiliation]"
The Impact of Hyperbaric Oxygen Therapy on Functional and Structural Plasticity in Rats With Spinal Cord Injury.
Brain Behav
December 2024
Department of Hyperbaric Oxygen, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Introduction: Spinal cord injury (SCI) can result in sensory and locomotor function loss below the injured segment. Hyperbaric oxygen therapy (HBOT) has been proven to alleviate SCI. This study aims to establish a reproducible rat model of SCI and investigate the impact of HBOT on alterations in brain neuronal activity and neuromotor function in this experimental rat SCI model using resting-state functional magnetic resonance imaging (rs-fMRI).
View Article and Find Full Text PDFAnticoagulant-associated calciphylaxis: analysis of USFDA adverse event report system and clinical feature analysis of reported cases.
Expert Opin Drug Saf
December 2024
Bahrain Defence Force Royal Medical Services, Riffa, Kingdom of Bahrain.
Background: Calciphylaxis is a serious, potentially fatal condition resulting in pathological calcification of soft tissues. While associated with chronic kidney disease, data regarding anticoagulant involvement remain limited.
Research Design And Methods: The United States Food and Drug Administration Adverse Event Reporting System (USFDA AERS) database was searched to identify calciphylaxis reports linked to anticoagulants from 2004 to 2024.
Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage.
N Engl J Med
December 2024
From Ottawa Hospital Research Institute, Ottawa (S.W.E., D.A.F., A.T., I.W., T.R., R.M., D.D., S.C.M., L.M.); the Department of Medicine, Division of Critical Care, Faculty of Medicine, University of Ottawa, Ottawa (S.W.E., L.M.); School of Epidemiology and Public Health University of Ottawa, Ottawa (S.W.E., D.A.F., L.M.); Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa (D.A.F., D.D., S.C.M.); George Institute for Global Health, Sydney (A.D., F.B., N.H., C.R.A., P.T.); Malcolm Fisher Department of Intensive Care Medicine, Royal North Shore Hospital, St. Leonards, NSW, Australia (A.D., N.H., C.R.A., E.F.); the Faculty of Medicine and Health, University of Sydney Northern Clinical School, St. Leonards, NSW, Australia (A.D., C.R.A.); Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, VIC, Australia (A.D., A.U.); the Department of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal (M. Chassé); the Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal (M. Chassé); the Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Faculty of Medicine, Université Laval, Quebec, QC, Canada (A.F.T., F.L.); Population Health and Optimal Health Practice Research Unit, Centre Hospitalier Universitaire de Québec-Université Laval Research Center, Quebec, QC, Canada (A.F.T., F.L.); the Department of Anesthesia, Critical Care Medicine Service, Hôpital de L'Enfant-Jésus, Centre Hospitalier Universitaire de Québec-Université Laval, Quebec, QC, Canada (A.F.T., F.L.); the Department of Medicine, Faculty of Medicine, Université Laval, Quebec, QC, Canada (F.L.); the Department of Neurology and Neurosurgery, Division of Neurocritical Care, Emory University School of Medicine, Emory University Hospital and Grady Memorial Hospital, Atlanta (O.S.); the Department of Medicine, Division of Critical Care Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, Canada (D.E.G.); the Division of Neurosurgery, Vancouver General Hospital, Vancouver, BC, Canada (G.R.); the Division of Neurosurgery, Department of Surgery, the University of British Columbia, Vancouver, Canada (G.R.); Neurocritical Care and Anesthesia, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto (M. Chapman); McGill University, Montreal (M.H.); the Departments of Critical Care Medicine and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.K.); Nepean Clinical School, University of Sydney, Sydney (I.S.); the Department of Clinical Medicine, Macquarie University, Sydney (I.S.); the Critical Care and Trauma Division, the George Institute for Global Health, Sydney (I.S.); the Department of Intensive Care and Hyperbaric Medicine, the Alfred, Melbourne, VIC, Australia (A.U.); the Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada (D.J.K.); the Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada (R.Z.); the Department of Medical Oncology/Hematology and the Paul Albrechtsen Research Institute, Cancer Care Manitoba, Winnipeg, Canada (R.Z.); the Department of Anesthesiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada (F.D.); Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada (F.D.); the Department of Medicine, Division of Neurology, School of Medicine, Queen's University, Kingston, ON, Canada (J.G.B.); Department of Critical Care Medicine, School of Medicine, Queen's University, Kingston, ON, Canada (J.G.B.); the Intensive Care Unit, Prince of Wales Hospital, Randwick, NSW, Australia (G.S.); the Department of Intensive Care, Royal Brisbane and Women's Hospital, Herston, QLD, Australia (J.B.); University of Queensland, Brisbane, Australia (J.B.); the Department of Adult Intensive Care, Island Health Authority, Victoria, BC, Canada (G.W.); University of Colorado School of Medicine, Aurora (L.C.); the Department of Surgery, Division of Neurosurgery, Dalhousie University, Halifax, NS, Canada (G.P.); QEII Health Sciences Centre, Halifax, NS, Canada (G.P.); Lewis Katz School of Medicine, Temple University, Philadelphia (L.K.); Rush University Medical Center, Chicago (L.K.); Royal North Shore Hospital, Sydney (F.B.); the Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto (D.C.S.); the Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto (D.C.S.); the Kirby Institute, University of New South Wales, Kensington, Australia (C.R.A.); the Department of Surgery, Division of Neurosurgery, Faculty of Medicine, University of Ottawa, Ottawa (J.S.); Canadian Blood Services, Edmonton, AB, Canada (J.A.); the Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada (J.A.); and Physical Medicine and Rehabilitation, Bruyere Continuing Care, Ottawa (S.C.M.).
Background: The effect of a liberal red-cell transfusion strategy as compared with a restrictive strategy in patients during the critical care period after an aneurysmal subarachnoid hemorrhage is unclear.
Methods: We randomly assigned critically ill adults with acute aneurysmal subarachnoid hemorrhage and anemia to a liberal strategy (mandatory transfusion at a hemoglobin level of ≤10 g per deciliter) or a restrictive strategy (optional transfusion at a hemoglobin level of ≤8 g per deciliter). The primary outcome was an unfavorable neurologic outcome, defined as a score of 4 or higher on the modified Rankin scale (range, 0 to 6, with higher scores indicating greater disability) at 12 months.
Comparative analysis of COVID-19-related mortality risk in chronic lower respiratory disease and interstitial lung disease.
Sarcoidosis Vasc Diffuse Lung Dis
December 2024
Division of Pulmonary, Critical Care, Hyperbaric, and Sleep Medicine, Department of Medicine, Loma Linda University Health, Loma Linda, California, USA.
An Evaluation of the Readability, Quality, and Content of Online Disaster Preparedness Materials for the Society.
Disaster Med Public Health Prep
December 2024
Medical Faculty, Department of Public Health, Eskisehir Osmangazi University, Eskisehir, Turkey.
Objectives: A useful way to prepare the public for disasters is to teach them where to get information. The purpose of this study is to evaluate the readability and appropriateness of the content of websites prepared for the public on disaster preparedness.
Methods: In September-October 2022, we evaluated 95 disaster preparedness websites (intended for the public) using the Ateşman Readability Index, JAMA criteria, DISCERN, and a new researcher-created content comparison form.
The anesthetic and recovery profiles of low-dose hypobaric mepivacaine and bupivacaine for spinal anesthesia in total hip and knee arthroplasty: a prospective observational study.
Can J Anaesth
December 2024
Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Article Synopsis
- Spinal anesthesia using low-dose hypobaric mepivacaine and bupivacaine is effective for quick mobilization and same-day discharge after hip and knee surgeries.
- Time to achieve sensory blockade was similar for both anesthetics, allowing surgeons to start operations without delays.
- Both anesthetics provided adequate pain relief with predictable recovery times, making them suitable for fast-track orthopedic procedures.
Outcomes of pregnant and post-partum patients admitted to the intensive care unit with COVID-19 in Australia: An analysis of SPRINT-SARI Australia.
Aust N Z J Obstet Gynaecol
December 2024
Department of Intensive Care and Hyperbaric Medicine, The Alfred, Melbourne, Victoria, Australia.
Background: Pregnant and post-partum (collectively peri-partum) women may be at increased risk of severe COVID-19 disease.
Aims: To describe the characteristics, interventions, and outcomes of peri-partum patients admitted to intensive care units (ICUs) in Australia with COVID-19.
Materials And Methods: We conducted a prospective, multicentre observational study using the SPRINT-SARI Australia database across 63 ICUs in Australia.
Ophthalmic complications of injectable facial fillers.
World J Clin Cases
December 2024
Department of Community Medicine, Patna Medical College, Patna 800004, Bihar, India.
The recently published mini-review article by Miotti is an effort to clarify various aspects regarding the choice between fat grafts and fillers in facial aesthetic surgery. One of the complications associated with the administration of fillers is the possibility of vascular injury and spread of the dermal filler into the orbit, causing unexpected effects at a site distant from that of the initial injection, including ophthalmoplegia, ptosis and even visual compromise. Acute vision loss following filler injection is a devastating complication, occurring in up to 0.
View Article and Find Full Text PDFClinical research framework proposal for ketogenic metabolic therapy in glioblastoma.
BMC Med
December 2024
Biology Department, Boston College, Chestnut Hill, MA, 02467, USA.
Article Synopsis
- Glioblastoma (GBM) is the deadliest brain tumor in adults, and current therapies are largely ineffective, which drives the need for new treatment strategies based on the tumor's metabolic needs, specifically glucose and glutamine.
- A ketogenic metabolic therapy (KMT) approach targets these metabolic pathways by combining dietary changes with specific drugs to limit glycolysis and glutaminolysis, while promoting the use of non-fermentable fuels like ketones and fatty acids.
- The glucose-ketone index (GKI) serves as a biomarker to monitor treatment effectiveness, aiming to create a more hostile environment for tumor growth and improve outcomes in GBM as well as potentially other cancer types reliant on similar metabolic pathways.
Characteristics and outcomes of adults with acute brain injuries admitted to intensive care units in Australia and New Zealand from 2013 to 2022.
Aust Crit Care
December 2024
Intensive Care Unit, Wellington Hospital, Wellington, New Zealand; Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. Electronic address:
Background: The characteristics and outcomes of patients with acute brain injuries admitted to the intensive care unit (ICU) in Australia and New Zealand (ANZ) are insufficiently described.
Objective: This study aimed to describe the epidemiology of acute brain injury in ICU patients in ANZ.
Methods: A binational retrospective cohort study was conducted using the ANZ Intensive Care Society Adult Patient Database.
Clinical team debriefing post-critical events: perceptions, benefits, and barriers among learners.
Front Med (Lausanne)
November 2024
Department of Medicine, School of Medicine, Loma Linda University Health, Loma Linda, CA, United States.
Article Synopsis
- This study examines the perceptions and experiences of healthcare professionals regarding team debriefings after critical events, aiming to understand their importance and identify areas for improvement.
- An anonymous survey was conducted among various healthcare students and residents in southern California and Michigan, assessing factors like demographics, emotional status, and the benefits and barriers associated with post-code debriefings.
- Results revealed that while a majority of participants experienced cardiac events, only a minority engaged in post-code debriefings, with nurses and attending physicians participating most frequently; these discussions averaged around nine minutes.
Sub-acute stroke demonstrates altered beta oscillation and connectivity pattern in working memory.
J Neuroeng Rehabil
December 2024
Departments of Physical Medicine and Rehabilitation, The First Affiliated Hospital, Zhejiang University School of Medicine, Building 6, 58 Chengzhan Road, Hangzhou, 310003, China.
Introduction: Working memory (WM) is suggested to play a pivotal role in relearning and neural restoration during stroke rehabilitation. Using EEG, this study investigated the oscillatory mechanisms of WM in subacute stroke.
Methods: This study included 48 first subacute stroke patients (26 good-recovery, 22 poor-recovery, based on prognosis after a 4-week period) and 24 matched health controls.
The impact of dual-enrolee (Medicare/Medicaid) status on venous leg ulcer outcomes: a retrospective study.
J Wound Care
December 2024
Donald and Barbara Zucker School of Medicine, Hofstra/Northwell, Hempstead, NY, US.
Article Synopsis
- The study aimed to analyze the impact of race, sex, comorbidities, and Medicaid status on health outcomes for patients with hard-to-heal venous leg ulcers (VLUs), comparing Medicare-only beneficiaries to Medicare/Medicaid dual-enrollees from October 2015 to October 2019.
- Using Medicare claims data, the research focused on treatment methods, demographic comparisons, and quantified outcomes like ulcer closure time and quality of life metrics, finding notable differences between the two groups.
- Results showed that dual-enrollees had a higher burden of comorbidities, greater representation from minority backgrounds, and significantly increased rates of emergency visits and cellulitis compared to Medicare-only enrollees, with early use of certain
Engineering Semiconducting Polymeric Nanoagonists Potentiate cGAS-STING Pathway Activation and Elicit Long Term Memory Against Recurrence in Breast Cancer.
Adv Mater
January 2025
Department of Hyperbaric Oxygen Medicine, Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Center for Geriatric, Shenzhen People's Hospital, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, Guangdong, 518020, P. R. China.
Article Synopsis
- - Triple-negative breast cancer has a "cold" microenvironment that resists current immunotherapy, but activating the STING pathway shows potential for improving treatment effectiveness.
- - The study combines photothermal therapy (PTT) using a semiconductor nano-agent (DPTT-Mn Lipo NPs) with innate immune responses to reprogram the immune-suppressive environment and enhance anti-tumor immunity.
- - This approach not only triggers cell death and activates immune cells but also works well with anti-PD-1 therapy to create lasting immune memory, helping to prevent tumor recurrence.
Carbon Monoxide Intoxication Leading to Crush Syndrome and Acute Renal Failure: A Case Report.
Cureus
October 2024
Intensive Care Unit, Kayseri City Training and Research Hospital, Kayseri, TUR.
Carbon monoxide (CO) poisoning is a common occurrence, typically resulting from exposure to CO emissions in enclosed spaces. CO is a colorless, odorless, and tasteless gas. In this case report, we present a 52-year-old male patient who developed crush syndrome and acute kidney injury following carbon monoxide (CO) intoxication.
View Article and Find Full Text PDFNovel Pharmacologic and Other Somatic Treatment Approaches for Posttraumatic Stress Disorder in Adults: State of the Evidence.
Am J Psychiatry
December 2024
National Center for PTSD, U.S. Department of Veterans Affairs, Washington, DC (Sippel, Hamblen, Kelmendi, Schnurr, Holtzheimer); Geisel School of Medicine at Dartmouth, Department of Psychiatry, Hanover, NH (Sippel, Hamblen, Schnurr, Holtzheimer); Northeast Program Evaluation Center, U.S. Department of Veterans Affairs, (Sippel); Department of Psychiatry, Yale University School of Medicine, New Haven, CT (Kelmendi); Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, New York, NY (Alpert); Department of Psychiatry and Human Behavior, Butler Hospital, Brown University, Providence, RI (Carpenter); Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda); Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus (Kraguljac); Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA (McDonald); Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, and Veterans Affairs Palo Alto Health Care System, Palo Alto, CA (Rodriguez); Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis (Widge); Dell Medical School, University of Texas at Austin, Austin (Nemeroff).
Posttraumatic stress disorder (PTSD) is a highly prevalent psychiatric disorder that can become chronic and debilitating when left untreated. The most commonly recommended first-line treatments for PTSD among adults are individual trauma-focused psychotherapies. Other evidence-based treatments include specific antidepressant medications and non-trauma-focused psychotherapies.
View Article and Find Full Text PDFCancer treatment-related xerostomia: basics, therapeutics, and future perspectives.
Eur J Med Res
November 2024
Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Golgasht Street, Tabriz, 51666, EA, Iran.
Article Synopsis
- Xerostomia, or dry mouth, significantly affects cancer patients' quality of life and is influenced by various cancer treatments.
- While numerous potential treatments have been suggested, such as salivary substitutes, stem cell therapies, and acupuncture, none are currently approved as effective.
- The review examines the causes, symptoms, and existing treatment options for cancer-related xerostomia, aiming to guide clinicians in providing personalized care while highlighting future research opportunities in this area.
Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study).
BMJ Open
November 2024
Subaquatic and Hyperbaric Medicine Unit, Emergency Service, Acute Medicine Department, Geneva University Hospitals, Geneva, Switzerland.
Introduction: Sickle cell disease (SCD) is one of the most common genetic diseases in the world, annually affecting approximately 310 000 births and causing >100 000 deaths. Vaso-occlusive crisis (VOC) is the most frequent complication of SCD, leading to bone pain, thoracic pain (acute chest syndrome) and/or abdominal spasms. It is the main cause of mortality in patients with SCD, reducing life expectancy.
View Article and Find Full Text PDFInterventions for the management of long covid (post-covid condition): living systematic review.
BMJ
November 2024
Department of Anesthesia, McMaster University, Hamilton, ON, Canada.
Objective: To compare the effectiveness of interventions for the management of long covid (post-covid condition).
Design: Living systematic review.
Data Sources: Medline, Embase, CINAHL, PsycInfo, Allied and Complementary Medicine Database, and Cochrane Central Register of Controlled Trials from inception to December 2023.
The interaction of adenosine and dopamine in modulating the consequences of central nervous system oxygen toxicity.
J Appl Physiol (1985)
January 2025
Department of Diving and Hyperbaric Medicine, PLA Naval Medical Center, Naval Medical University, Shanghai, People's Republic of China.
Hyperbaric oxygen (HBO) refers to pure oxygen with a pressure greater than 1 atmospheres absolute (ATA), and when the pressure is too high, it can cause convulsive attacks. Adenosine and dopamine have been shown to be closely associated with HBO-induced convulsion seizures, and their receptors exhibited a coexisting relationship of mutual antagonism on the membrane of nerve cells. We explored the influence of adenosine and dopamine interplay on the occurrence of oxygen convulsion.
View Article and Find Full Text PDFEffect of Hyperbaric Oxygen Therapy on Patients with SARS-CoV-2 Infection: A Retrospective Cohort Study.
J Multidiscip Healthc
November 2024
Department of Rehabilitation Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Objective: The aim of this study was to evaluate the impact of hyperbaric oxygen therapy (HBOT) on patients with SARS-CoV-2 infection and determine its efficacy and safety in reducing treatment failure events.
Methods: A retrospective cohort study involving patients with COVID-19 was conducted. Inverse probability of treatment weighting (IPTW) was used to balance covariates between the HBOT and non-HBOT groups.
Hyperbaric Oxygen Therapy Ameliorates Olanzapine-Induced Hypolocomotion in a Rat Model.
Life (Basel)
November 2024
Department of Veterinary Basic Sciences, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
Olanzapine (OLZ) is a commonly prescribed drug for the treatment of schizophrenia and related disorders. However, OLZ use is associated with several adverse effects, including decreased locomotor activity and increased body weight. While the majority of studies have directed their focus towards managing the metabolic side effects of OLZ, there has been limited attention given to the effects on locomotor activity.
View Article and Find Full Text PDFCharacteristics of Side Effects in Non-Emergency Indications Using Computer-Controlled Pressurized Monoplace Hyperbaric Chambers: A Retrospective Multicenter Study.
J Clin Med
November 2024
Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Gangwon State, Republic of Korea.
Hyperbaric oxygen therapy (HBOT) involves inhaling nearly 100% oxygen in a pressurized environment and is commonly used to treat various diseases and injuries. Despite its well-known safety, HBOT is associated with side effects, with frequent middle ear barotrauma (MEB) and oxygen toxicity. Understanding the characteristics and risk factors associated with these side effects is critical for improving patient compliance and treatment outcomes.
View Article and Find Full Text PDFN exchanges in hyperbaric environments: toward a model based on physiological gas transport (O and CO).
J Appl Physiol (1985)
February 2025
ORPHY Laboratory, Université de Brest, Brest, France.
Decompression sickness can occur in divers even when recommended decompression procedures are followed. Furthermore, the physiological state of individuals can significantly affect bubbling variability. These informations highlight the need for personalized input to improve decompression in SCUBA diving.
View Article and Find Full Text PDFNutrition delivery during hospitalisation after critical illness in Australia and New Zealand: a multicentre, prospective observational study.
J Hum Nutr Diet
February 2025
Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.
Article Synopsis
- Critically ill patients in Australia and New Zealand often don't meet energy and protein targets with oral nutrition, especially compared to those who start enteral or parenteral nutrition in ICU.
- The study analyzed data from 409 patients across 44 hospitals to compare outcomes, focusing on energy delivery and nutrition assessment during hospital stays.
- Results showed that patients on oral nutrition had lower energy and protein intake, fewer invasive interventions, and received less nutrition assessment compared to those who switched to enteral or parenteral nutrition.