4 results match your criteria: "Department of Hematopoietic Stem Cell Transplantation National Cancer Center Hospital Tokyo Japan.[Affiliation]"
fusion is found in < 1% of de novo acute myeloid leukemia (AML) cases and confers a poor prognosis. This Japanese nationwide survey analyzed patients with AML ( = 22) and mixed phenotype acute leukemia (MPAL) ( = 10) with t(9;22) or who underwent allogeneic hematopoietic cell transplantation (allo-HCT) between 2002 and 2018. The 3-year overall survival (OS) rates were 81.
View Article and Find Full Text PDFWe herein report a case of peripheral blood stem cell transplantation (PBSCT) involving a donor with EDTA-induced pseudothrombocytopenia (PTCP). The apheresis product was inspected for 24 h and there was no platelet clumping or thrombocytopenia. In the first 14 months after PBSCT, there has been no transfer of PTCP symptoms.
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- The study analyzed outcomes of 151 acute myeloid leukemia (AML) patients with the rare genetic alteration der(1;7)(q10;p10) after undergoing allogeneic hematopoietic stem cell transplantation (allo-SCT).
- Results showed that patients with der(1;7)(q10;p10) had significantly better transplant outcomes compared to 853 patients with monosomy 7 or chromosome 7q deletion (-7/del(7q)).
- Factors like additional chromosomal abnormalities and poor performance status were found to impact survival in the der(1;7)(q10;p10) group, indicating that allo-SCT is a viable treatment option for these patients.
Alectinib, an anaplastic lymphoma kinase (ALK) inhibitor, as a bridge to allogeneic stem cell transplantation in a patient with ALK-positive anaplastic large-cell lymphoma refractory to chemotherapy and brentuximab vedotin.
Clin Case Rep
December 2019
Department of Hematology National Cancer Center Hospital Tokyo Japan.
This is the first case report of alectinib as a bridge to allo-SCT in a patient with ALK-positive ALCL refractory to both conventional chemotherapies and BV. This report offers a ray of hope for a condition with poor prognosis.
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