A study conducted in Nagano, Japan, identified five cases of pregnancy-associated leukemia out of 377,000 pregnancies over 20 years, indicating a rare occurrence of one case in every 75,000 pregnancies.
All cases were types of acute leukemia, with timely diagnoses made during the first, second, and third trimesters of pregnancy.
Treatment involved chemotherapy in three cases with positive outcomes for two newborns, while high-risk cases had poor outcomes, highlighting the need for specialized, multidisciplinary care for managing leukemia during pregnancy.
A rare case of a germ cell tumor transformed into a malignant form was reported, specifically a testicular primitive neuroectodermal tumor with multiple metastases.
The patient, a 22-year-old man, underwent surgery, radiation, and chemotherapy after being diagnosed with a teratoma and initially responding to first-line treatment.
After experiencing a recurrence of skull metastasis, a successful second-line chemotherapy led to no disease progression three months later, highlighting the potential for effective multidisciplinary cancer treatment in such rare cases.