The study analyzed outcomes of 151 acute myeloid leukemia (AML) patients with the rare genetic alteration der(1;7)(q10;p10) after undergoing allogeneic hematopoietic stem cell transplantation (allo-SCT).
Results showed that patients with der(1;7)(q10;p10) had significantly better transplant outcomes compared to 853 patients with monosomy 7 or chromosome 7q deletion (-7/del(7q)).
Factors like additional chromosomal abnormalities and poor performance status were found to impact survival in the der(1;7)(q10;p10) group, indicating that allo-SCT is a viable treatment option for these patients.