Nilotinib is a type of medication used to block a specific protein (BCR-ABL) involved in cancer, but it also affects how other drugs are metabolized in the body by inhibiting the enzyme CYP3A4.
Because it can raise the levels of other drugs that are processed by CYP3A4, healthcare providers need to be cautious when prescribing these medications to patients taking nilotinib.
After a transplant, patients treated with nilotinib require close monitoring of their drug levels to ensure safe and effective use of immunosuppressive medications.