The relationship between malocclusion and speech patterns: a cross-sectional study.

Objective: Dental occlusion and the alignment of the dentition play crucial roles in producing speech sounds. The Arabic language is specifically complex, with many varieties and geographically dependent dialects. This study investigated the relationship between malocclusion and speech abnormalities in the form of misarticulations of Arabic sounds.

Longitudinal Trends in Physical Activity Among Older Adults With and Without HIV in Uganda.

Introduction: Physical Activity (PA) and its links to frailty, quality of life (QoL), and other comorbidities in older Ugandans living with HIV remain under-explored.

Methods: We analyzed data from three annual assessments of older people living with HIV (PLWH) and age- and sex-similar people not living with HIV (PnLWH). We fitted linear generalized estimating equations (GEE) regression models to estimate the correlates of PA, including demographics, frailty, QoL, HIV, and other comorbidities.

Current Trends in Endodontic Clinical Practice in Croatia: A Report From a Croatian National Survey.

Objective: To assess the state of endodontic practices and identify factors influencing the use of modern endodontic techniques among dental practitioners in Croatia.

Materials And Methods: A questionnaire was distributed to all dental offices in Croatia, yielding 819 responses (27% response rate). Data were descriptively analyzed and statistically modeled.

Long-term success and survival of post-endodontic restorations without posts after up to 18 years: A practice-based study.

Objectives: The aim of this non-interventional, multi-center, prospective, practice-based study was, firstly, to evaluate the longevity of composite build-ups in endodontically treated teeth, treated with root canal therapy (ETT), without post placement and secondly, to identify and analyze factors influencing the success of these reconstructions.

Methods: Each of seven general dental practitioners placed up to 50 composite build-ups without additional posts in ETT. Teeth were restricted to incisors, canines and premolars.

Kotter's change management approach to transforming oral healthcare delivery: A case study.

Introduction: Despite progress in research and technological advancements, the delivery of oral health care continues to be plagued by disparities in accessibility and affordability. Dental caries and periodontal disease remain major issues, and new challenges such as socioeconomic disparities and emerging public health dangers also contribute to the complexity of the issue. To address these challenges, dental education and oral healthcare delivery must shift their focus from disease treatment to disease prevention and health promotion.

Transient apical breakdown associated with clear aligner therapy: a case report.

Transient apical breakdown (TAB) is widely reported in response to trauma, yet its occurrence due to orthodontic forces, particularly in aligner therapy, is less documented within current literature. TAB can easily be misdiagnosed as pulp necrosis, potentially leading to unnecessary and irreversible endodontic procedures. This case report describes an instance of TAB following the initiation of aligner treatment, where the affected tooth initially presented with signs suggesting pulp necrosis but regained normal coloration and pulpal response after six months of active monitoring.

SNOMED-CT and learning health systems for NHS dentistry - a dream needing to become reality.

There has been discussion and confusion about SNOMED-CT (systematised nomenclature of medicine clinical terminology), learning health systems (LHSs) and their relevance in dentistry. This article aims to provide an overview of SNOMED-CT, LHSs and the all-too-often omitted patient and service benefits from their use. LHSs are delivering impactful benefits to patients and services globally in medicine.

Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 3: solid cancers and vascular abnormalities.

This study discusses disseminated intravascular coagulation (DIC) associated with solid cancers and various vascular abnormalities, both of which generally exhibit chronic DIC patterns. Solid cancers are among the most significant underlying diseases that induce DIC. However, the severity, bleeding tendency, and progression of DIC vary considerably depending on the type and stage of the cancer, making generalization difficult.

Characteristics and impact of pain from root-filled teeth. A practice-based cross-sectional study comparing painful teeth with and without signs of inflammatory dental disease.

To compare pain characteristics, impact of pain and characteristics of patients with painful root-filled teeth with and without signs of inflammatory dental disease. This cross-sectional study was performed in the Public Dental Health services, Region Örebro County, Sweden. Adult patients with ≥1 root-filled tooth identified at their regular check-up were included and assigned to one of two groups; those with ≥1 sign of inflammatory dental disease (DD+) and those without any such sign (DD-).

Stress and Stressors Among PHCC Dentists: A Quantitative, Correlational, and Cross-Sectional Study.

(1) Background: Dentistry is innately stressful and demanding. However, the extent of perceived chronic stress and the contributing factors within the dental practice at Primary Health Care Corporation (PHCC) in Qatar are largely unknown. (2) Methods: This study is quantitative, hypothesis-testing, correlational, and cross-sectional, using a simple random sample of all PHCC dentists (168 general dentists and 47 specialist dentists).

Development and Evaluation of a GPT4-Based Orofacial Pain Clinical Decision Support System.

: Orofacial pain (OFP) encompasses a complex array of conditions affecting the face, mouth, and jaws, often leading to significant diagnostic challenges and high rates of misdiagnosis. Artificial intelligence, particularly large language models like GPT4 (OpenAI, San Francisco, CA, USA), offers potential as a diagnostic aid in healthcare settings. : To evaluate the diagnostic accuracy of GPT4 in OFP cases as a clinical decision support system (CDSS) and compare its performance against treating clinicians, expert evaluators, medical students, and general practitioners.

Target product profile for cell-based and gene-based therapies to achieve a cure for HIV.

This target product profile (TPP) highlights the minimal and optimal characteristics for ex-vivo and in-vivo cell and gene therapy-based products aimed at achieving an HIV cure (ie, durable antiretroviral-free viral control). The need for an effective, safe, scalable, affordable, accessible, and acceptable cure for HIV infection remains a major global priority. The possibilities for cell and gene therapy-based products for an HIV cure are rapidly expanding.

Adult orthodontic consultations in private dental practice: How much information do patients remember when they leave the surgery?

Objective: With good communication and information retention being key aspects of valid consent, this study aimed to assess adult patient information recall immediately after an orthodontic consultation.

Materials And Methods: Adults interested in bracket-based or clear aligners were invited to take part at a single private dental practice. A 45-minute consultation with one of three general dental practitioners (GDPs) primarily providing orthodontics took place.

The Use of Social Media on Enhancing Dental Care and Practice Among Dental Professionals: Cross-Sectional Survey Study.

Background: As digitalization continues to advance globally, the health care sector, including dental practice, increasingly recognizes social media as a vital tool for health care promotion, patient recruitment, marketing, and communication strategies.

Objective: This study aimed to investigate the use of social media and assess its impact on enhancing dental care and practice among dental professionals in the Philippines.

Methods: A cross-sectional survey was conducted among dental practitioners in the Philippines.

Association between vascular endothelial growth factor and atrial fibrillation: a systematic review.

Background: Atrial fibrillation (AF) is the most prevalent form of sustained cardiac arrhythmia, with vascular endothelial growth factor (VEGF) increasingly recognized for its potential role in the pathogenesis of AF through mechanisms involving atrial remodeling, inflammation, and fibrosis. This systematic review aims to synthesize available evidence on the association between VEGF and AF, exploring the implications of VEGF as a biomarker and therapeutic target.

Methods: We conducted a comprehensive search across PubMed, Embase, and Web of Science until November 10 2024, selecting studies based on pre-defined criteria that involve adults with AF and measurements of VEGF levels.

Knowledge, Attitude, and Practice of Dutch Dentists on Oral Leukoplakia and Their Possible Role in Its Follow-Up.

Objective: To assess the knowledge, attitude, and practice of Dutch dentists on oral leukoplakia (OL) and to what extent these aspects are related to whether or not dentists regularly monitor patients with OL.

Material And Methods: A self-developed questionnaire was distributed via a web survey among a sample of dentists participating in an intervision program. Of 1626 invited dentists, 437 (26.

CAD-CAM complete digital dentures: An improved clinical and laboratory workflow.

The purpose of this article was to present a novel clinical workflow for the fabrication of complete dentures using computer-aided design and computer-aided manufacturing (CAD-CAM) technology. The dental technique consists of 3 clinical steps and 2 laboratory phases that result in the production of 2 CAD-CAM milled complete denture bases with prefabricated teeth. The integration of analog and digital procedures and materials maximizes their benefits in the planning and fabrication of complete dentures, with the goal of improving clinical outcomes.

Evaluation of dentists' clinical practices and antibiotic use in managing endodontic emergencies in Karachi, Pakistan: a cross-sectional survey.

Background: Endodontic emergencies, often presented as acute pain or swelling, constitute a substantial challenge in dental practice. While effective management emphasizes prompt intervention, antibiotics are typically indicated only when systemic signs and symptoms are present. There is limited research exists on evaluating the knowledge and clinical approach of dental practitioners in managing endodontic emergencies from our region of the world.

Evaluation of Marginal Fit of CAD/CAM Ceramic Crowns and Scanning Time Using Different Intraoral Scanning Systems.

This study aimed to evaluate the scanning time and marginal fit of CAD/CAM crowns fabricated using different intraoral scanning systems (IOS) (O1-Omnicam 1.0, O2-Omnicam 2.0, PS-Primescan).

Artificial Intelligence and Modern Technology in Dentistry: Attitudes, Knowledge, Use, and Barriers Among Dentists in Croatia-A Survey-Based Study.

Aim: This study aims to assess Croatian dentists' knowledge, attitudes, and use of artificial intelligence (AI) and modern technology, while also identifying perceived barriers to AI and modern technology adoption and evaluating the need for further education and training.

Materials And Methods: A cross-sectional survey was conducted in February 2024 among general dentists in Croatia using a self-structured questionnaire. A total of 200 respondents filled out the questionnaire.

Surface Characterization of Bone-Level and Tissue-Level PEEK and Titanium Dental Implant Scan Bodies After Repeated Autoclave Sterilization Cycles.

Sterilization is required for any biomedical device intended to be used in contact with the human body. Several studies have reported alterations in the bulk and surface properties of such devices after repeated sterilization cycles. These surface modifications may influence other clinical parameters.

Anti-diabetic therapies on dental implant success in diabetes mellitus: a comprehensive review.

Background And Objective: Dental implant therapy faces challenges in patients with Type 1 and Type 2 Diabetes Mellitus (T1DM and T2DM) due to adverse effects on bone metabolism and immune response. Despite advancements, diabetic patients face higher risks of peri-implantitis and compromised osseointegration. This review assesses the impact of anti-diabetic medications on implant outcomes, offering insights to bridge the gap between animal studies and clinical practice.

Awareness of Melanoma and Skin Self-Examination at a Tertiary Care Hospital in Pakistan: A Study of Knowledge, Attitudes, and Practices.

Background Melanoma, the most lethal form of skin cancer, contributes to a majority of skin cancer fatalities globally. It carries a grim prognosis with a high propensity for early metastasis. People are not aware of moles, their natural course of progression, and skin self-examination.

Glucocorticoid tapering pace in microscopic polyangiitis and granulomatosis with polyangiitis in Japanese real-world practice: A propensity score-matched retrospective cohort study from the J-CANVAS registry.

Objective: To assess the prevalence and outcomes among regimens of glucocorticoid tapering for microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) in real-world practice.

Methods: We retrospectively examined the Japan Collaborative Registry of ANCA-associated Vasculitis (J-CANVAS) registry, and evaluated the prevalence of glucocorticoid tapering regimens in the PEXIVAS trial. In patients with newly diagnosed MPA and GPA, we compared outcomes among standard and reduced pace regimens.