A study was conducted to evaluate the safety and effectiveness of enoxaparin for preventing venous thromboembolism (VTE) after hepatobiliary-pancreatic cancer surgery, which is often overlooked due to bleeding risks.
In a prospective trial involving 262 patients across eight centers, participants were randomized to receive enoxaparin or no treatment for 8 days post-surgery.
Results showed a non-significant reduction in VTE cases with enoxaparin and no difference in bleeding events, indicating that while enoxaparin is safe, more research is needed to fully understand its effectiveness for this patient group.