2 results match your criteria: "Department of Endocrinology of the Air Force Medical Center[Affiliation]"
Characteristic gene prognostic model of type 1 diabetes mellitus via machine learning strategy.
Endocr J
March 2023
Department of Endocrinology of the Air Force Medical Center, People's Liberation Army, Beijing 100142, China.
Article Synopsis
- The study aims to find biomarkers for Type 1 diabetes (T1DM) to help in developing new treatments.
- Researchers analyzed mRNA expression data from blood cells of T1DM patients and healthy individuals, identifying 60 immune-related differentially expressed genes (DEGs) and narrowing them down to three key hub genes: ANP32A-IT1, ESCO2, and NBPF1.
- The analysis highlighted significant immune cell differences between T1DM and normal samples and showed that the identified hub genes have strong diagnostic potential, with high area under curve (AUC) values exceeding 0.8.
This study aims to establish a diagnostic model of coronary heart disease (CHD) for diabetic foot (DF) patients.The clinical data of 489 hospitalized patients with DF were retrospectively analyzed in this case-control study. The patients were divided into the CHD group (DF with CHD, n = 212) and the control group (DF without CHD, n = 277).
View Article and Find Full Text PDF