Central Hypothyroidism: Advances in Etiology, Diagnostic Challenges, Therapeutic Targets, and Associated Risks.

Central hypothyroidism is a rare condition characterized by insufficient production of thyroid hormones by the thyroid gland caused by defects in TSH secretion from the pituitary or TRH secretion from the hypothalamus. Its etiology includes genetic and acquired causes, mainly associated with tumors in the hypothalamic-pituitary region or treatments such as surgery and radiotherapy. This review discusses advances in its etiology, diagnosis, and treatment, with a focus on diagnostic and therapeutic challenges.

Cross-cultural validation and Spanish translation of the Boston Interview to evaluate severely obese patients seeking metabolic/bariatric surgery.

Introduction: obesity is a global health problem. Metabolic/Bariatric surgery (MBS) has proven to be one of the most effective methods for treating the most severe forms. However, a thorough evaluation and preparation of people seeking MBS is necessary.