Phage M198 and Its Therapeutic Potential.

The rapid worldwide spread of antibiotic resistance is quickly becoming an increasingly concerning problem for human healthcare. Non-antibiotic antibacterial agents are in high demand for many Gram-negative bacterial pathogens, including . -targeting phages are among the most promising alternative therapy options.

The Frequency of c.557A>G in the Dominican Population and Its Association with African Ancestry.

Genetic polymorphism of the dihydropyrimidine dehydrogenase gene () is responsible for the variability found in the metabolism of fluoropyrimidines such as 5-fluorouracil (5-FU), capecitabine, or tegafur. The genotype is linked to variability in enzyme activity, 5-FU elimination, and toxicity. Approximately 10-40% of patients treated with fluoropyrimidines develop severe toxicity.

Species Diversity, Biomass Production and Carbon Sequestration Potential in the Protected Area of Uttarakhand, India.

Ecosystem functioning and management are primarily concerned with addressing climate change and biodiversity loss, which are closely linked to carbon stock and species diversity. This research aimed to quantify forest understory (shrub and herb) diversity, tree biomass and carbon sequestration in the Binsar Wildlife Sanctuary. Using random sampling methods, data were gathered from six distinct forest communities.

Central Asia Cold Case: Siberian Pine Fingers New Suspects in Growth Decline CA 1700 CE.

Tree-ring width chronologies of Du Tour from near the upper treeline in the Western Sayan, Southern Siberia are found to have an exceptional (below mean-3SD) multi-year drop near 1700 CE, highlighted by the seven narrowest-ring years in a 1524-2022 regional chronology occurring in the short span of one decade. Tree rings are sometimes applied to reconstruct seasonal air temperatures; therefore, it is important to identify other factors that may have contributed to the growth suppression. The spatiotemporal scope of the "nosedive" in tree growth is investigated with a large network of (14 sites) and Ledeb.

- Essential Oil: Chemical Composition, Phytotoxic Activity and Environmental Safety.

Weeds cause a decrease in the quantity and quality of agricultural production and economic damage to producers. The prolonged use of synthetic pesticides causes problems of environmental pollution, the possible alteration of agricultural products and problems for human health. For this reason, the scientific community's search for products of natural origin, which are biodegradable, safe for human health and can act as valid alternatives to traditional herbicides, is growing.

Red Currant ( L.) Fruit Waste Extract and Juice as Potential Spasmolytic Agents.

Red currant ( L.) berries are rich in bioactive compounds and exhibit nutritive and protective features. This research examined the content of secondary metabolites of the red currant variety Redpoll lyophilized juice and waste extract and their antioxidative and spasmolytic effects.

Different Genotypes of the Rare and Threatened Moss (Funariaceae) Exhibit Different Resilience to Zinc and Copper Stress.

The funarioid moss species , which is threatened with extinction, was the subject of this study. The riparian habitat type of this species is often under the influence of contaminated water, and, therefore, we tested the influence of selected potentially toxic elements (PTEs), namely zinc and copper, on the development, physiological features, and survival of the species on two different accessions (German and Croatian). The results obtained showed the different resilience of the two accessions to the PTEs.

Combined Impact of Canada Goldenrod Invasion and Soil Microplastic Contamination on Seed Germination and Root Development of Wheat: Evaluating the Legacy of Toxicity.

The concurrent environmental challenges of invasive species and soil microplastic contamination increasingly affect agricultural ecosystems, yet their combined effects remain underexplored. This study investigates the interactive impact of the legacy effects of Canada goldenrod ( L.) invasion and soil microplastic contamination on wheat ( L.

Chemical Characterization and Differential Lipid-Modulating Effects of Selected Plant Extracts from Côa Valley (Portugal) in a Cell Model for Liver Steatosis.

Background/objectives: Côa Valley, located in the northeast of Portugal, harbors more than 500 medicinal plant species. Among them, four species stand out due to their traditional uses: Desf. (hemorrhages, urethritis, hepatitis), L.

Assessment of Antibiotic Resistance Among Isolates of spp. and spp. in Wildlife and Their Environment from Portugal: A Positive Epidemiologic Outcome.

One of the significant challenges facing modern medicine is the rising rate of antibiotic resistance, which impacts public health, animal health, and environmental preservation. Evaluating antibiotic resistance in wildlife and their environments is crucial, as it offers essential insights into the dynamics of resistance patterns and promotes strategies for monitoring, prevention, and intervention. and genera isolates were recovered from fecal samples of wild animals and environmental samples using media without antibiotic supplementation.

Inferring Tripartite Associations of Vector-Borne Plant Pathogens Using a Next-Generation Sequencing Approach.

Phytoplasmas are a group of plant-pathogenic, cell-wall-less bacteria vectored primarily by leafhoppers (Hemiptera Cicadellidae), one of the most diverse families of insects. Despite the importance of documenting associations between phytoplasmas, their insect vectors, and plant hosts to prevent disease outbreaks, such knowledge is currently highly incomplete and largely neglects the diversity of the system in natural areas. Here, we used anchored hybrid enrichment (AHE) to recover the DNA of five plant genes (, , , , and ) in 58 phloem-feeding leafhoppers from around the world that had previously tested positive for phytoplasma infection.

Detection and Whole-Genome Characteristics of Isolated from Captive Snakes.

is a rare member of the genus , primarily associated with human wound infections rather than respiratory diseases. The bacterium has been isolated from various clinical specimens, including ear inflammatory discharge, diabetic ulcers, and chronic wounds. The study aimed to characterize the genomes and antimicrobial resistance (AMR) profiles of obtained from the fecal samples of asymptomatic highland eyelash pit vipers ().

Characterization of Esocid Herpesvirus 1 (EsHV1) from Europe.

During routine sampling of northern pike, a male with circular blue-metallic granular spots mainly located on the head and back was identified. Histological investigations presented multifocally thickened epidermis rich in basophilic large structures with a granulated rim and a dense, non-granulated center. Other organs showed no signs of infection.

Spatial Characterization of Woody Species Diversity in Tropical Savannas Using GEDI and Optical Data.

Developing the capacity to monitor species diversity worldwide is of great importance in halting biodiversity loss. To this end, remote sensing plays a unique role. In this study, we evaluate the potential of Global Ecosystem Dynamics Investigation (GEDI) data, combined with conventional satellite optical imagery and climate reanalysis data, to predict in situ alpha diversity (Species richness, Simpson index, and Shannon index) among tree species.

Association Between Lower Limb Strength Asymmetry and Gait Asymmetry: Implications for Gait Variability in Stroke Survivors.

: Gait disturbances characterized by asymmetries in lower limb strength and gait patterns are frequently observed in stroke patients, which increases gait variability and fall risk. However, the extent to which lower limb strength asymmetry influences gait asymmetry and variability in this population remains unclear. : This cross-sectional study included 84 participants, comprising stroke survivors and age- and sex-matched healthy older adults.

Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention.

In recent years, the near-infrared (NIR) fluorescence theranostic system has garnered increasing attention for its advantages in the simultaneous diagnosis- and imaging-guided delivery of therapeutic drugs. However, challenges such as strong background fluorescence signals and rapid metabolism have hindered the achievement of sufficient contrast between tumors and surrounding tissues, limiting the system's applicability. This study aims to integrate the pegylation strategy with a tumor microenvironment-responsive approach.

Nontarget Catches of Green and Brown Lacewings (Insecta: Neuroptera: Chrysopidae, Hemerobiidae) Collected by Light- and Volatile-Baited Traps in the Transcarpathian Lowland (W Ukraine).

Distribution data on the lacewing fauna of the data-deficient Transcarpathian Lowland (West Ukraine) were provided. The attractivity of phenylacetaldehyde-(FLO) and isoamyl alcohol-based (SBL) lures designed for trapping lepidopteran pests to lacewings was also studied and compared to the efficiency of light traps traditionally used in studies on neuropterans. In the three-year study, 374 individuals of 10 species were caught.

A Review on the Nomenclature and Taxonomy of the Old World Thread-Legged Bug Genus (Hemiptera: Reduviidae: Emesinae).

The nomenclatural and taxonomic issues regarding the thread-legged bug genera Kirkaldy, 1901 and Bergroth, 1903 are reviewed, and is concluded to be the valid name of the genus. A comprehensive review of is conducted, resulting in 18 new combinations and two new synonymies [ (Villiers, 1970) , (Ghate, Boyane & Joshi, 2019) , (Bergroth, 1903) , (McAtee & Malloch, 1926) , (Paiva, 1919) , (Lhoste, 1939) = Miller, 1956 , (Kulkarni & Ghate, 2016) , (Ribes, 1987) , (Lhoste, 1939) , (McAtee & Malloch, 1926) , (Villiers, 1972) , (Wygodzinsky, 1966) , (Wygodzinsky, 1966) , (Distant, 1906) , (Villiers, 1970) , (Horváth, 1910) , (Villiers, 1949) = Miller, 1954 , and (Rédei, 2005) ]. The bibliographies, diagnosis, and known distribution records are presented for all described species, and three new species [ (from Yunnan, China), (from Sabah, Malaysia), and (from Sulawesi, Indonesia)] are described.

Thermal Melanism in (Coleoptera: Scarabaeidae: Cetoniinae).

Thermal polymorphism, usually represented by thermal melanism (darker coloration in cooler habitats), is a well-known phenomenon in animals. In Cetoniinae, several species in captivity tend to become darker after several generations of breeding, which is probably caused by a lower temperature than is typical for their native habitats. is a beetle species occurring in Somaliland.

Characterizing Stream Condition with Benthic Macroinvertebrates in Southeastern Minnesota, USA: Agriculture, Channelization, and Karst Geology Impact Lotic Habitats and Communities.

Prior to implementing watershed-wide projects to reduce the impacts of agriculture on regional streams and rivers, stream habitats and benthic aquatic macroinvertebrate communities were assessed at 15 sites on the South Branch Root River and its major tributaries in southeastern Minnesota, USA. Triplicate kick-net samples were collected from each site during three time periods (1998, 1999, 2006/2008) and stream habitats were inventoried within 150 m long sections at each site. In total, 26,760 invertebrates representing 84 taxa were collected and used to rate stream sites using a regional multi-metric benthic index of biotic integrity (BIBI).

, a New Genus of the Tarsonemid Tribe Pseudotarsonemoidini (Acari: Heterostigmatina) from Mexico.

A new genus for the tribe Pseudotarsonemoidini of the family Tarsonemidae is established in order to accommodate undescribed mites associated with bark beetles in Mexico. The new, monotypic genus , with the type species being diagnostically and phylogenetically closest to the derived - cluster of the Pseudotarsonemoidini, possesses an intermediate position between these two genera. Details of the morphology related to its genus-level affiliation, primarily tibiotarsal I claw and leg setation, are compared in the context of the other genera of the tribe.

Utilization of Cannabidiol in Post-Organ-Transplant Care.

Cannabidiol (CBD) is one of the major phytochemical constituents of cannabis, , widely recognized for its therapeutic potential. While cannabis has been utilized for medicinal purposes since ancient times, its psychoactive and addictive properties led to its prohibition in 1937, with only the medical use being reauthorized in 1998. Unlike tetrahydrocannabinol (THC), CBD lacks psychoactive and addictive properties, yet the name that suggests its association with cannabis has significantly contributed to its public visibility.

Intermediates of Hydrogen Peroxide-Assisted Photooxidation of Salicylic Acid: Their Degradation Rates and Ecotoxicological Assessment.

Accelerated photooxidation of salicylic acid (SA) was performed using UV radiation and hydrogen peroxide. HPLC-MS analysis showed that the primary intermediates are 2,5-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid, pyrocatechol, and phenol. Deeper oxidation leads to low molecular weight aliphatic acids, such as maleic, fumaric, and glyoxylic.

Comparative Efficacy of Melatonin and Brassinolide in Mitigating the Adverse Effects of Cadmium on .

Melatonin (MT) and brassinolide (BL) are phytohormones that regulate various physiological processes in plants. This study investigates their effects on when exposed to cadmium (Cd). Plant hormones were quantified using liquid chromatography-mass spectrometry, while photosynthetic pigments and phytochelatins (PCs) were analyzed through high-performance liquid chromatography.

Combined Transcriptomics and Metabolomics Uncover the Potential Mechanism of Plant Growth-Promoting Rhizobacteria on the Regrowth of After Mowing.

Mowing significantly influences nutrient cycling and stimulates metabolic adjustments in plants to promote regrowth. Plant growth-promoting rhizobacteria (PGPR) are crucial for enhancing plant growth, nutrient absorption, and stress resilience; however, whether inoculation with PGPR after mowing can enhance plant regrowth capacity further, as well as its specific regulatory mechanisms, remains unexplored. In this study, PGPR (B13) was inoculated into mowed to evaluate its effects on phenotypic traits, root nutrient contents, and hormone levels during the regrowth process and to further explore its role in the regrowth of after mowing.