Monitoring Nystagmus in a Patient With Vertigo Using a Commercial Mini-Infrared Camera and 3D Printer: Cost-Effectiveness Evaluation and Case Report.

Background: Observing eye movements during episodic vertigo attacks is crucial for accurately diagnosing vestibular disorders. In clinical practice, many cases lack observable symptoms or clear findings during outpatient examinations, leading to diagnostic challenges. An accurate diagnosis is essential for timely treatment, as conditions such as benign paroxysmal positional vertigo (BPPV), Ménière's disease, and vestibular migraine require different therapeutic approaches.

Case Report of a Primary Sinonasal Renal Cell-Like Adenocarcinoma With Gene Rearrangement in a 13-Year-Old Male.

Background: Sinonasal renal cell-like adenocarcinoma (SNRCLA) is a rare, low-grade malignant neoplasm originating in the nasal cavity and paranasal sinuses. This report provides a detailed account of the clinical and pathological characteristics of a single case of SNRCLA, highlights its differential diagnosis, and includes a review of relevant literature.

Case Description: A 13-year-old male presented with a mass in the right nasal cavity.

Skip Metastasis in a Pediatric Patient with Medullary Thyroid Cancer: A Case Report and a Review of the Literature.

Skip metastasis in thyroid cancer occurs when there is lateral neck lymph node involvement of tumor without central neck lymph node involvement. Here, cancer spreads to the lateral neck while "skipping" more proximal central neck nodes. While this unusual pattern of spread has been previously described in adults with thyroid cancer, to our knowledge it has never been described in children.

Orbital Apex Syndrome Caused by Herpes Zoster Ophthalmicus Following Nasal Endoscopic Surgery: A Case Report.

Orbital apex syndrome (OAS) is a severe orbital condition caused by impairment of cranial nerves after inflammation or local compression. The report details an uncommon case of OAS caused by herpes zoster ophthalmicus (HZO) following endoscopic sinus surgery. A 52-year-old male exhibited symptoms of OAS in the postoperative phase; however, imaging examination and endoscopic evaluations failed to support that surgical damage and bacterial infection were the cause.

Cutaneous Allodynia and Photophobia in Vestibular Migraine and Other Vestibular Disorders: A Prospective Study in a Tertiary Centre.

Introduction: Photophobia (PP) and cutaneous allodynia (CA) are sensory sensitivity symptoms recognised as features of migraine. The prevalence of PP and CA in vestibular migraine (VM) and other vestibular disorders (OVD) is unknown.

Aim: The aim of this study is to measure the prevalence of PP and CA in VM compared with OVD.

Prioritisation of head, neck, and respiratory outcomes in mucopolysaccharidosis type II: lessons from a rare disease consensus exercise and comparison of parental and clinical priorities.

Background: The mucopolysaccharidoses are a group of rare, inherited metabolic disorders. MPS II is a X-linked recessive disease, also known as Hunter syndrome. Clinical manifestations include upper and lower respiratory tract, and head and neck pathologies influencing quality of life, morbidity, and mortality.

[Prediction of future language proficiency in Mandarin-speaking cochlear implant recipients based on early childhood vocabulary proficiency].

The objective of this longitudinal study is to longitudinally monitor the lexical development and language proficiency of Mandarin-speaking children with cochlear implants (CI) over a three-year post-implantation period while also investigating whether early receptive and expressive vocabulary skills can serve as predictors for later language abilities in CI recipients. In this study, 42 children with CIs were selected as participants, including 19 males and 23 females, and with a mean age at CI activation of 16.6±4.

Identification of age-related metabolomic signatures in vascular tissues.

Vascular aging contributes to the morbidity and mortality in older individuals, closely linked to an imbalance between energy consumption and production. Despite its importance, our understanding of how aging affects vascular metabolism and leads to vascular diseases remains limited. In this study, we explored the metabolomic characteristics of vascular aging by analyzing aortic tissues from young and old mice through untargeted metabolomic analysis using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).

Determinants of a longer length of stay in major head and neck cancer surgery: A national study based on the French hospital discharge database.

Background: In many countries where hospitals are funded by a prospective payment scheme based on Diagnosis Related Groups (DRG), two risks may arise whenever legitimate extra costs are not considered: patient selection and/or lower care quality. We aimed to analyse determinants of an increased length of stay (LOS) used as a proxy for costs, in major head and neck cancer surgery.

Methods: We selected all hospitalisations in France between 2015 and 2021 classified in the DRG « Major head and neck surgery », with a main diagnosis of cancer.

Down-regulation of PCK2 enhanced the radioresistance phenotype of nasopharyngeal carcinoma.

Purpose: Radiotherapy is the main treatment for non-distant metastatic nasopharyngeal carcinoma (NPC). However, about 15% of NPC patients still experience local tumor recurrence after radiotherapy. The mechanisms underlying the radioresistance of NPC have not been fully understood.

Minimally Invasive Surgery for Retropharyngeal Infiltrative Intramuscular Lipoma: Report of a Case Treated Using a Combined Transoral and Transnasal Approach.

Retropharyngeal infiltrative intramuscular lipomas are rare, and only 2 cases have been reported. Surgical resection is technically challenging owing to anatomical constraints, with no established optimal approach. Furthermore, the risk of recurrence is high.

Glomangiopericytoma of Sinonasal Cavity: Case Report of a Rare Entity.

Glomangiopericytoma is an uncommon tumor of the sinonasal region, originating from the pericytes that envelop capillaries, and it accounts for fewer than half a percent (0.5%) of all sinonasal tumors. This report presents the case of a 65-year-old man who experienced worsening nasal obstruction and was subsequently diagnosed with glomangiopericytoma based on histological, immunohistochemical, and radiographic findings.

Balloon dilatation of the Eustachian tube for obstructive Eustachian tube dysfunction in adults.

Background: Eustachian tube dysfunction (ETD) causes symptoms and signs of pressure dysregulation in the middle ear, and is associated with tympanic membrane retraction, otitis media with effusion, and chronic otitis media. Interventions aiming to improve symptoms can be non-surgical or surgical, including balloon dilatation of the Eustachian tube, also known as balloon eustachian tuboplasty (BET) for obstructive ETD. However, existing published evidence for the effectiveness and safety of BET remains unclear.

Typical and atypical metabolic characteristics of three iridaceae isoflavone components: and studies.

Background: (L.) DC (Chinese name Shegan) has been widely used because of its pharmacological activity and remarkable therapeutic effects in sore throat. Tectorigenin, irigenin, and irisflorentin have been recognized as important quality indicators in Shegan.

The Prevalence and Management of Aerodigestive Foreign Bodies at Rwanda Military Hospital: A Six-years Retrospective Study.

Background: Aerodigestive foreign bodies are common issue especially in children, who often place objects in their mouths, leading to inhalation or ingestion. Despite global data on this issue, no comprehensive study has been conducted in Rwanda. This study aimed to assess the prevalence, demographic factors, clinical presentations, diagnostic and management techniques of aerodigestive foreign bodies at Rwanda Military Hospital (RMH).

Exploring benefits of speech and language therapy interventions for post-stroke aphasia rehabilitation: A qualitative study.

Background: The ability to understand and use language is impacted in people with aphasia, often requiring Speech and language therapy interventions to improve their ability to communicate. Currently, there is limited information concerning the experiences of people with aphasia who have undergone speech therapy in many countries such as Ghana where the practice of speech and language therapy is still in its infancy. Such knowledge is known to enhance the uptake of speech and language therapy services and improve both quality and reach.

Rescue Tracheal Reconstruction via Platysma Myocutaneous Flap Following Necrosis of Sternocleidomastoid Muscle Myoperiosteal Flap.

A case of a 60-year-old male patient with thyroid cancer invading the trachea was presented in the current study. After the initial surgery via a sternocleidomastoid muscle (SCM) clavicular periosteal flap for tracheal reconstruction, the patient experienced flap necrosis. Subsequent debridement and tracheocutaneostomy were performed, followed by a successful repair of the tracheal defect using a platysma myocutaneous flap.

Antibiotic Use Can be De-escalated During Transoral Endoscopic Thyroidectomy: A Bacterial Culture-Based Study.

To explore the possibility of reducing the use of antibiotics after transoral endoscopic thyroidectomy vestibular approach (TOETVA). A retrospective study was conducted on patients with thyroid tumors who were diagnosed and underwent surgical treatment at our hospital from 2022 to 2024. Patients diagnosed with T1-stage differentiated thyroid cancer or a benign retrosternal goiter <4 cm with cosmetic needs were included in the current study.

WAYS TO IMPROVE THE RESULTS OF SURGICAL TREATMENT OF DIFFUSE TOXIC GOITER.

Introduction: This article discusses the prevention of intraoperative complications in the surgical treatment of diffuse toxic goiter. The above complications push surgeons to find a more optimal method of surgical treatment.

Aim: Development of new methods to reduce the risk of intraoperative complications in the surgical treatment of patients with diffuse toxic goiter.

Stereoselective Synthesis and Antimicrobial Studies of -Gibberic Acid-Based 2,4-Diaminopyrimidine Chimeras.

: Gibberellins (GAs) are a family of tetracyclic -kaurenoid diterpenes found widely in several commonly used plants. Besides agricultural applications, gibberellins play an important role in the synthesis of bioactive compounds, especially those with antiproliferative and antibacterial activity. : A series of gibberellic acid-based 2,4-diaminopyrimidines was designed and synthesized from commercially available gibberellic acid.

Management of Deep Neck Infection Associated with Descending Necrotizing Mediastinitis: A Scoping Review.

Deep neck infection is a pathology at the border of two specialties, otorhinolaryngology and maxillofacial surgery, and represents a medico-surgical emergency. In terms of its evolution, it can extend to the level of the thorax and result in mediastinitis, with difficult evolution and poor prognosis. The aims of this scoping review are to present the etiology, bacteriology, clinical manifestations, and diagnostics, as well as treatment, in light of the research published in the last 5 years on deep neck infection associated with descending necrotizing mediastinitis.

Determinants of Acute Otitis Media in Children: A Case-Control Study in West Java, Indonesia.

: Acute Otitis Media (AOM) is a leading cause of morbidity in children, characterized by fever, otalgia, and hearing loss. If untreated, AOM may progress to chronic complications requiring surgical management. Globally, factors such as allergies, environmental tobacco smoke, and nutritional deficiencies are well-established risk factors, but in Indonesia, particularly rural areas like Bandung Regency, limited awareness and data exacerbate the burden of disease.