Facial Fillers and Surgical Rhinoplasty: Cross-Sectional Study.

This study aims to provide an overview of how rhinoplasty surgeons manage patients with previous nonsurgical rhinoplasty and facial fillers. A multicenter international cross-sectional study was conducted in accordance with strengthening the reporting of observational studies in epidemiology (STROBE) guidelines. A survey was distributed to members of the European Academy of Facial Plastic Surgery and associated colleagues, with responses analyzed from surgeons performing over 10 rhinoplasties annually.

Noise-induced hearing loss in Turkish special forces personnel.

Noise-induced hearing loss is a significant occupational hazard for police personnel. Intense noise from training and military activities can permanently damage the inner ear, leading to hearing loss. The aim of this study is to compare the hearing of Turkish Special Forces personnel with that of healthy individuals.

Deep transfer learning radiomics for distinguishing sinonasal malignancies: a preliminary MRI study.

Purpose: This study aimed to assess the diagnostic accuracy of combining MRI hand-crafted (HC) radiomics features with deep transfer learning (DTL) in identifying sinonasal squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC), and non-Hodgkin's lymphoma (NHL) using various machine learning (ML) models.

Methods: A retrospective analysis of 132 patients (50 with SCC, 42 with NHL, 40 with ACC) was conducted. The dataset was split 80/20 into training and testing cohorts.

Pretreatment and Posttreatment Prospective Evaluation of Smell and Taste Dysfunction in Children With Attention Deficit Hyperactivity Disorder.

Objective: This study investigated whether attention-deficit hyperactivity disorder (ADHD) has an olfactory dysfunction and, if so, the effect of methylphenidate on this condition.

Methods: The "Sniffin" Sticks Test and a questionnaire were applied to 50 children with ADHD and 50 healthy children as the control group before and after being treated with methylphenidate.

Results: There was a statistical difference between ADHD and control groups in odor sensitivity, odor discrimination skills, and odor identification tests ( < .

Respiratory dysfunction in whiplash associated disorders (WAD) with cervical plexus syndrome - A case report.

Whiplash Associated Disorders (WAD) represents a chronic post-traumatic pain syndrome from indirect flexion-extension trauma to the neck. The condition exhibits significant variability among affected individuals and can involve numerous secondary symptoms, including but not limited to myalgia, central sensitization, migraines, photophobia, jaw pain, dysphagia, joint stiffness, and tinnitus, while significant breathing problems are not commonly associated with or prominently considered in WAD. Herein, we present the diagnosis and successful surgical treatment of severe respiratory dysfunction and staccato speech in a patient with WAD, who over a period of more than ten years underwent multiple spirometry evaluations for breathing difficulties that correlated with the severity of neck pain.

Successful Management of a Keratoconus Patient With Rarely Used Large-Diameter Corneal RGP Contact Lenses: A Case Report.

Keratoconus is a degenerative corneal disease that is usually bilateral and asymmetric. In keratoconus, the cornea progressively thins and steepens, leading to vision impairment. This unique case report highlights the management of a keratoconus patient with infrequently used large-diameter corneal RGP contact lenses.

A scoping review of ear and hearing health research in Aotearoa New Zealand: a focus on equity.

A recommendation from a series of Aotearoa New Zealand (NZ) ear and hearing health hui was to summarise literature in ear, hearing, and vestibular health to inform future strategic directions. We aimed to conduct a scoping review of ear, hearing, and vestibular health literature in NZ over the past 50 years, with a particular focus on equity research in underserved communities. The review was undertaken using PRISMA guidelines and managed using Covidence.

Estimation of the pattern of ocular manifestations, risk factors, and imaging of rhino-orbital-cerebral mucormycosis in COVID-19 patients.

Purpose: To estimate the pattern of ocular manifestations, as observed clinically and radiologically, and associated risk factors in cases of coronavirus disease 2019 (COVID-19)-related rhino-orbital cerebral mucormycosis (ROCM) during the second wave at presentation to the hospital in northern India.

Materials And Methods: A total of 35 patients of ROCM associated with active cases of COVID-19 or recovered cases of COVID-19 presenting to the Ophthalmology outpatient department or admitted in the COVID ward of the hospital with clinical features suggestive of ROCM. They were confirmed as mucormycosis on KOH and fungal cultures of nasal scrapings and histopathology of debrided tissue.

Deregulation of Exosomal miR-17, miR-20a and TGFBR2 in Head and Neck Cancer Patients.

Exosomes play significant roles in transferring cargo materials like proteins, RNAs (including miRNAs), and DNA. However, the role of serum exosome shuttled RNAs and miRNAs in head and neck cancer (HNC) remains unclear. This study assessed the diagnostic and prognostic significance of exosomal , , and in HNC patients.

Chronic Sinonasal Inflammation as a Comorbidity of Respiratory Epithelial Adenomatoid Hamartoma: A 15-Year Retrospective Observational Study.

Respiratory epithelial adenomatoid hamartoma (REAH) is a benign pseudo-glandular proliferation of the nasal cavity with poorly-understood etiopathogenesis. This study aimed to examine the frequency of comorbidities in patients with REAH and to determine whether comorbidity affects the clinical characteristics of REAH. A retrospective cohort study included patients with REAH treated at 2 university hospitals over 15 years.

Middle Turbinate Vascular Malformation Associated With Angiofibroma Originating From the Nasal Septum: A Case Report.

According to the latest classification of vascular lesions, cavernous hemangioma is considered a venous or arteriovenous malformation. The literature has not described the association between vascular malformation of the middle turbinate and angiofibroma of the nasal septum. A 26-year-old female patient with profuse left-sided bleeding and nasal obstruction is presented.

Retinal vascular alterations in cognitive impairment: A multicenter study in China.

Introduction: Foundational models suggest Alzheimer's disease (AD) can be diagnosed using retinal images, but the specific structural features remain poorly understood. This study investigates retinal vascular changes in individuals with cognitive impairment in three East Asian regions.

Methods: A multicenter study was conducted in Shanghai, Hong Kong, and Ningxia, collecting retinal images from 176 patients with mild cognitive impairment (MCI) or AD and 264 controls.

Phosphatidylserine as a tumor target for CAR-T cell therapy.

Background: Phosphatidylserine (PS) exposed on apoptotic cells promotes immune clearance of dead cells without inducing inflammation. Conversely, PS exposure on live tumor cells promotes an immunosuppressive tumor microenvironment that hinders antitumor immune responses. After confirming elevated PS levels in various tumor cell lines and cancer tissues, we aimed to investigate its potential as a target antigen for chimeric antigen receptor T cell (CAR-T) therapy.

Transforming pediatric ENT documentation: Efficiency, accuracy, and adoption of speech recognition technology (Speaknosis).

Introduction: Efficient and accurate medical documentation ensures patient safety, continuity of care, and clinician satisfaction. Speech recognition technology has emerged as a promising alternative to traditional documentation methods, potentially reducing administrative burden and improving workflow efficiency. However, concerns about accuracy, consistency, and clinical adoption remain significant barriers to its integration into medical practice.

Effect of vestibular rehabilitation treatment (VRT) on patients with unsteadiness after intratympanic gentamicin in Menière's disease: protocol for a randomised controlled trial.

Introduction: Menière's disease (MD) is a multifactorial disease characterised by recurring vertigo, tinnitus and fluctuating sensorineural hearing loss as typical clinical symptoms. For patients with MD with poor response to non-invasive treatments, it is recommended to use intratympanic gentamicin treatment. The destruction of vestibular organs by gentamicin may cause residual vestibular symptoms, notably unsteadiness.

Consensus for a postoperative atlas of sinonasal substructures from a modified Delphi study to guide radiotherapy in sinonasal malignancies.

Background: Sinonasal and skull base tumor surgery-related morbidity has been reduced by the use of endoscopic endonasal skull base surgery (EESBS). Postoperative radiation therapy (poRT) requires precise definition of target volumes. To enhance the accuracy of poRT planning, histological and radiological correlations are necessary to locate the tumor attachment on poRT CT scans.

Deep learning models for differentiating three sinonasal malignancies using multi-sequence MRI.

Purpose: To develop MRI-based deep learning (DL) models for distinguishing sinonasal squamous cell carcinoma (SCC), adenoid cystic carcinoma (ACC) and olfactory neuroblastoma (ONB) and to evaluate whether the DL models could improve the diagnostic performance of Senior radiologist (SR) and Junior radiologist (JR).

Methods: This retrospective analysis consisted of 465 patients (229 sinonasal SCCs, 128 ACCs and 108 ONBs). The training and validation cohorts included 325 and 47 patients and the independent external testing cohort consisted of 93 patients.

Ultra-high-resolution CT of the temporal bone: Technical aspects, current applications and future directions.

Temporal bone imaging has historically suffered from spatial resolution issues because the spatial resolution of conventional high-resolution computed tomography (CT) is 0.5 mm, while the smallest structure of the middle ear, the stapes, has very thin components, as thin as 0.19 mm, and small structures, such as small channels containing nerves and arteries, have historically been beyond its spatial resolution.

Novel progressive rod-cone degeneration mutation causes retinitis pigmentosa.

Retinitis pigmentosa (RP) is a genetic disorder often caused by single or multiple mutations. The progressive rod-cone degeneration (PRCD) gene is linked to retinal degeneration. This study identified a family affected by RP carrying a frameshift mutation (c.

Remission in chronic rhinosinusitis with nasal polyps (CRSwNP).

Remission has recently been proposed as the new goal of care in CRSwNP or Nasal Polyp Syndrome by the European Forum for Research and Education in Allergy and Airway Diseases / European Position Paper on Rhinosinusitis and Nasal Polyps (EUFOREA/EPOS) (1,2) as well as by global leaders in Rhinology (3). In CRSwNP, remission is defined as a prolonged state of control, without bothersome symptoms reported by the patient for at least 12 months, without the need for either oral corticosteroids or endoscopic sinus surgery (ESS), and without endoscopic signs of active disease (1). This new goal of care is to be encouraged by the ENT community and CRSwNP patients as persistent symptoms unalleviated by historical approaches (4,5) can be reduced by new therapies including biologics.

Complex of intratumoral mycobiome and bacteriome predicts the recurrence of laryngeal squamous cell carcinoma.

Unlabelled: Dysbiosis of intratumoral fungal and bacterial communities is associated with poor prognosis in various cancers. However, the mycobiome characteristics in laryngeal squamous cell carcinoma (LSCC) and its correlation with recurrence have not yet been investigated. The mycobiome in 80 LSCC samples was characterized using internal transcribed spacer sequencing, encompassing both tumor tissues and their matched para-cancerous tissues.

Discrepancies in Beta-Lactam Antibiotics Cross-Reactivity: Implications for Clinical Practice.

Background: In patients with a beta-lactam antibiotic (BA) allergy label, avoidance of the whole group of BAs leads to displacement of first-line therapies potentially influencing patient outcomes and antimicrobial resistance. Studies previously published on BA cross-reactivity use different sets of BA and seem to contain conflicting recommendations on safe BA alternatives in case of (suspected) BA allergy.

Methods: The objectives were (i) to identify discrepancies between studies regarding cross-allergy in BA and (ii) to identify research gaps.

Severity, Age, Sex, Sleep, Anxiety, and Their Correlation Analysis of 1739 Tinnitus Patients.

Objective: To prevent and reduce the incidence of tinnitus and to relieve the suffering of those with existing tinnitus.

Study Design: A study was conducted using a questionnaire.

Setting: Large number of patients come to ENT because tinnitus is seriously affecting their lives, and we found that these patients have some common factors that influence the development of this condition.