2 results match your criteria: "Department of Dermatology Rutgers New Jersey Medical School Newark New Jersey USA.[Affiliation]"
Introduction: Exosomes are extracellular vesicles that transport bioactive substances during normal and abnormal cellular physiological processes. The unique properties of exosomes can be exploited for use as biomarkers and targeted drug delivery vehicles, and are, for this reason, gaining increasing attention in the field of dermatology. This review aims to synthesise the existing evidence supporting exosomes in regenerative and cosmetic dermatology.
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- - Pemphigus is a serious autoimmune blistering disease that significantly impacts patients' health and quality of life, prompting numerous clinical trials to explore effective treatments.
- - A review of 53 randomized clinical trials showed that the Pemphigus Disease Area Index is the most commonly used disease severity measure, particularly gaining traction after 2015, while less popular methods have declined.
- - There's a growing trend toward including Quality of Life (QoL) measurements in clinical trials, although only a quarter currently assess it; standardizing these measures can improve data interpretation and clinical relevance over time.